Bio-Rad mouse anti human C4c,mouse anti human C4c-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Bio-Rad mouse anti human C4c,mouse anti human C4c

2024-10-22

mouse anti human C4c

货号：MCA2608

规格：0.1 mg

价格：6248

产品类型：流式抗体

品牌：Bio-Rad

抗原：C4c

物种：人

宿主：小鼠

抗体亚型：IgG1

克隆号：033D-69.4.1 (10-12)

荧光染料：Purified

产品介绍
Mouse anti Human C4c antibody, clone 033D-69.4.1 (10-12)recognizes complement component 4c (C4c). The complement 1 complex cleaves complement 4 (C4) to form C4b and C4a. C4b levels are strictly regulated. Single site cleavage of the C4b’s alpha chain by Factor I forms iC4b and blocks C3 convertase, inhibiting opsonisation and activation of the classical pathway. iC4b is further degraded into the inactive fragments C4d and C4c. C4c consists of two a-chain fragments, alpha 4 (13 kDa) and alpha 3 (25 kDa) linked to a beta chain through disulphide bridges and a gamma chain. It is expressed in the blood plasma.
产品详情
Target Species	Human
Product Form	Purified Ig - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein A from ascites
Buffer Solution	Borate buffered saline
Immunogen	Purified human C4c.
Approx. Protein Concentrations	Current, batch-specific concentration 1.15 mg/ml
Preservative Stabilisers	0.09%Sodium Azide (NaN3)
Regulatory	For research purposes only
Guarantee	Guaranteed until date of expiry. Please see product label.
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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Description	Product Code	Applications	Pack Size
Mouse IgG1 Negative Control	MCA928	F	100 Tests/1ml
文献
1.Press, E.M. & Gagnon, J. (1981) Human complement component C4. Structural studies on the fragments derived from C4b by cleavage with C3b inactivator.Biochem J. 199 (2): 351-7.2.Leung, E.et al.(2006) The complement regulator C4b-binding protein (C4BP) interacts with both the C4c and C4dg subfragments of the parent C4b ligand: evidence for synergy in C4BP subsite binding.Biochemistry. 45 (27): 8378-92.

技术参数

产品应用 Flow;IHC(F);WB;ELISA

产品类型单克隆抗体

推荐用于 Flow;IHC(F);WB;ELISA

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Bio-Rad mouse anti human C4c,mouse anti human C4c

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