BIO-RAD MCA2516F Mouse anti Human CD87 antibody, clone VIM-5 ,Mouse anti Human CD87 antibody, clone VIM-5

2024-10-22

Mouse anti Human CD87 antibody, clone VIM-5

货号:MCA2516F

规格:0.1 mg

价格:2907

产品类型:流式抗体

品牌:Bio-Rad

抗原:CD87

物种:人

宿主:小鼠

抗体亚型:IgG1

克隆号:VIM-5

荧光染料:FITC

产品介绍
Mouse anti Human CD87 antibody, clone VIM-5recognizes human CD87, also known as urokinase plasminogen activator receptor (uPAR), a 50-65 kDa single chain glycosylphostidylinsitol (GPI) anchored glycoprotein, expressed by granulocytes, tissue macrophages, monocytes, endothelial cells, fibroblasts and mesenchymal and epithelial tumour cells.CD87 specifically binds and activates urokinase plasminogen activator (uPA), a serine protease which converts the inactive receptor-bound proenzyme plasminogen into plasmin, triggering the proteolysis cascade of fibrinolysis. The interaction between uPAR and uPA is also known to play a role in cancer cell invasion and metastasis.Clone VIM-5 is reported to block urokinase binding.
产品详情
Target SpeciesHuman
Product FormPurified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
PreparationPurified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.09%Sodium Azide (NaN3)1%Bovine Serum Albumin
Max Ex/EmFluorophoreExcitation Max (nm)Emission Max (nm)
FITC490525
Approx. Protein ConcentrationsIgG concentration 0.1mg/ml
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application NameVerifiedMin DilutionMax Dilution
Flow Cytometry
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Sillaber, C.et al.(1997) Molecular and functional characterization of the urokinase receptor on human mast cells.J Biol Chem. 272 (12): 7824-32.2.Gadd, S.J.et al.(1990) M5, a phosphoinositol-linked human myelomonocytic activation-associated antigen.Clin Exp Immunol. 80 (2): 252-6.

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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