Bio-Rad mouse anti SYK MCA2383,Mouse anti Human Syk antibody, clone SYK-01

2024-10-22

Mouse anti Human Syk antibody, clone SYK-01

货号:MCA2383

规格:0.1 mg

价格:2015

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:Syk

物种:人

宿主:小鼠

抗体亚型:IgG1

克隆号:SYK-01

荧光染料:Purified

产品介绍
Mouse anti Human Syk antibody, clone SYK-01recognizes protein tyrosine kinase p72syk(syk), a ~72kDa non-receptor tyrosine kinase, critical for immunoreceptor signaling in haematopoietic cells, but also expressed by nonhaematopoietic cells, including fibroblasts, endothelial cells and hepatocytes.Syk plays an important role in mast cell response, initiated by the aggregation of the IgE high affinity receptor Fc epsilon R1. Phosphorylation of ITAMs within Fc receptor R1 by another tyrosine kinase lyn, results in the recruitment of syk, which is then responsible for the further phosphorylation of numerous target proteins within many different signal transduction pathways.Syk also plays a major role in B cell receptor-mediated apoptosis, proliferation and haematopoiesis. Syk associates with protein kinase C alpha during platelet activation.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationPurified IgG prepared by affinity chromatography on Protein G
Buffer SolutionPhosphate buffered saline
ImmunogenRecombinant fragment corresponding to amino acids 5 - 360 of human syk.
Approx. Protein ConcentrationsIgG concentration 1.0 mg/ml
Preservative Stabilisers<0.1% Sodium Azide (NaN3)
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application NameVerifiedMin DilutionMax Dilution
Immunoprecipitation
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Tolar, P.et al. (1997) Protein tyrosine kinase Syk is involved in Thy-1 signaling in rat basophilic leukemia cells.Eur J Immunol. 27(12): 3389-3397。

技术参数

产品应用 IP;WB

产品类型 单克隆抗体

推荐用于 IP;WB

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