BIO-RAD MCA2245PB Rat anti Mouse CD41 antibody, clone MWReg30,Rat anti Mouse CD41 antibody, clone MWReg30

2024-10-22

Rat anti Mouse CD41 antibody, clone MWReg30

货号:MCA2245PB

规格:100 Tests/1ml

价格:2533

产品类型:流式抗体

品牌:Bio-Rad

抗原:CD41

物种:小鼠

宿主:大鼠

抗体亚型:IgG1

克隆号:MWReg30

荧光染料:Pacific Blue

产品介绍
Rat anti Mouse CD41 antibody, clone MWReg30recognizes the mouse integrin alpha IIb subunit CD41. CD41 is a ~125 kDa single pass type 1 transmembrane glycoprotein expressed by platelets, megakaryocytes (Zhanget al.2007), mast cells (Berlangaet al.2005), and hematopoietic progenitors (Mitjavila-Garciaet al.2002). CD41 forms a heterodimer withCD61.The CD41/CD61 complex is important for platelet adhesion and aggregation (Patelet al.2003) acting as a receptor for many extracellular matrix proteins including fibronectin, thrombospondin and vitronectin (Weiselet al.1992).Rat anti mouse CD41, clone MWReg30 has been reported to inhibit PMA induced aggregationin vitroand to induce hypothermiain vivo(Nieswandtet al.1999).
产品详情
Target SpeciesMouse
Product FormPurified IgG conjugated to Pacific Blue - liquid
PreparationPurified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.09% Sodium Azide (NaN3)1% Bovine Serum Albumin
Approx. Protein ConcentrationsIgG concentration 0.05 mg/ml
Max Ex/EmFluorophoreExcitation Max (nm)Emission Max (nm)
Pacific Blue®410455
ImmunogenPurified murine platelets
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.
应用
Application NameVerifiedMin DilutionMax Dilution
Flow CytometryNeat
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
文献
1.Nieswandt, B.et al.(1999) Acute systemic reaction and lung alterations induced by an antiplatelet integrin gpIIb/IIIa antibody in mice.Blood. 94 (2): 684-93.

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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