BIO-RAD MCA2244GA Rat anti Mouse Lymphotoxin beta Receptor antibody, clone 5G11b,Rat anti Mouse Lymphotoxin beta Receptor ant

2024-10-22

Rat anti Mouse Lymphotoxin beta Receptor antibody, clone 5G11b

货号:MCA2244GA,MCA2244

规格:0.1 mg,0.25 mg

价格:2482,3043

产品类型:流式抗体

品牌:Bio-Rad

抗原: Lymphotoxin beta Receptor

物种:小鼠

宿主:大鼠

抗体亚型:IgG1

克隆号:5G11b

荧光染料:Purified

产品介绍
Rat anti Mouse Lymphotoxin beta Receptor antibody, clone 5G11brecognizes murine Tumor necrosis factor receptor superfamily member 3, also known as lymphotoxin-beta receptor, LT beta R, or Tumor necrosis factor receptor superfamily member 3. Lymphotoxin beta receptor is 385 amino acid (415 aa including 30 aa signal peptide) ~50 kDa type 1, single pass transmembrane glycoprotein and member of the tumor necrosis factor family. LT beta R is primarily expressed on stromal cells and fibroblasts and at lower levels on myeloid cell lines. Rat anti Mouse Lymphotoxin beta Receptor antibody, clone 5G11b recognizes surface expressed LT beta R.Rat anti Mouse Lymphotoxin beta Receptor antibody, clone 5G11b is reported to be agonistic with respect to NF Kappa B activation, MIP-2 induction and IL-6 release (Hehlganset al.2003).Rat anti Mouse Lymphotoxin beta Receptor antibody, clone 5G11b is routinely tested on WEH164S cells.
产品详情
Target SpeciesMouse
Product FormPurified IgG - liquid
PreparationPurified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer SolutionPhosphate buffered saline
Approx. Protein ConcentrationsIgG concentration 1.0 mg/ml
Fusion PartnersSpleen cells from immunised Wistar rats were fused with cells of the SP2/0 - Ag14 mouse myeloma cell line.
Preservative Stabilisers0.09%Sodium Azide
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application NameVerifiedMin DilutionMax Dilution
Flow Cytometry
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Hehlgans Tet al.(2003) Activation of the lymphotoxin-beta receptor induces NFkappaB-dependent interleukin-6 and MIP-2 secretion in mouse fibrosarcoma cells.Eur Cytokine Netw. 14 (2): 103-7.

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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