BIO-RAD MCA2059PE Mouse anti Human CD88 antibody, clone P12/1,Mouse anti Human CD88 antibody, clone P12/1-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

BIO-RAD MCA2059PE Mouse anti Human CD88 antibody, clone P12/1,Mouse anti Human CD88 antibody, clone P12/1

2024-10-22

Mouse anti Human CD88 antibody, clone P12/1

货号：MCA2059PE

规格：100 Tests

价格：3188

产品类型：流式抗体

品牌：Bio-Rad

抗原：CD88

物种：人

宿主：小鼠

抗体亚型：IgG2a

克隆号：P12/1

荧光染料：PE

产品介绍
Mouse anti Human CD88 antibody, clone P12/1recognizes the C5a receptor (C5aR) also known as CD88 or C5a anaphylatoxin chemotactic receptor 1. CD88 is predominantly expressed on cells of the myeloid lineage.When C5aR is preincubated with C5a, Mouse anti Human CD88 antibody, clone P12/1 does not bind to the receptor, as the binding site of P12/1 is located in the C5a binding region (Werfelet al. 1996andWeinmanet al. 2003)
产品详情
Target Species	Human
Product Form	Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilized
Reconstitution	Reconstitute with 1.0 ml distilled waterCare should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution.
Preparation	Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.09% Sodium Azide (NaN3)1% Bovine Serum Albumin5% Sucrose
Fusion Partners	Spleen cells from immunised BALB/c mice were fused with cells of the mouse X63 - Ag8 myeloma cell line.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
Prior to reconstitution store at +4℃. Following reconstitution store at +4℃.DO NOT FREEZE.This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Werfel, T.et al. (1996) CD88 antibodies specifically bind to C5aR on dermal CD117+ and CD14+ cells and react with a desmosomal antigen in human skin.J Immunol. 157: 1729-35.2Opperman, M.et al. (1995) Antibodies from the myeloid panel that react with the C5a receptor and anatagonize C5a biological activity.In: Schlossman, S.F. (ed.) Leucocyte Typing V. OUP: 955-6.3.Pollok-Kopp Bet al.(2007) Dynamics of protein kinase C-mediated phosphorylation of the complement C5a receptor on serine 334.J Biol Chem. 282 (7): 4345-53.

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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BIO-RAD MCA2059PE Mouse anti Human CD88 antibody, clone P12/1,Mouse anti Human CD88 antibody, clone P12/1

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