Mouse anti Human CD31:StarBright Violet 515

货号：MCA1738SBV515

规格：100 Tests/0.5ml

价格：3808

产品类型：流式抗体

品牌：Bio-Rad

物种：人

宿主：小鼠

抗体亚型：IgG1

荧光染料：StarBright Violet 515

类型：	单抗	同型对照：	IgG1
浓度：		用法：	5.0 µL/test(Flow)
免疫原性：

Mouse anti Human CD31 monoclonal antibody, clone WM59recognizes the human CD31 antigen, a ~130 kDa single pass type I transmembrane glycoprotein bearing sixC2 immunoglobulin domains. CD31 is expressed by all continuous endothelia including arteries, veins and non-sinusoidal capillaries, platelets,granulocytes and some lymphocytes. CD31 is not expressed by discontinuous endothelia such as hepatic sinusoids and splenic red pulp (Mulleret al.1989).CD31 is also known as PECAM-1.The binding epitope for mouse anti human CD31, clone WM59 has been mapped to the Ig-like domain 2 (Fawcettet al.1995).

数据：

Figure A. FITC conjugated Mouse anti Human CD31 (MCA1738F). Figure B. FITC conjugated Mouse anti Human CD31 (MCA1738F) and SBV515 conjugated Mouse anti Human CD105 (MCA1557SBV515). All experiments performed on HUVECs gated on live single cells, in the presence of 10% human serum. Data acquired on theZE5 Cell Analyzer.

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参考文献：

1.Cabañas, C.et al.(1989) Characterization of a novel myeloid antigen regulated during differentiation of monocytic cells.Eur J Immunol. 19 (8): 1373-8.2.Fawcett, J.et al. (1995) Mapping the homotypic binding sites in CD31 and the role of CD31 adhesion in the formation of interendothelial cell contacts.J Cell Biol. 128:1229-41.3.Paul, G.et al.(2012) The adult human brain harbors multipotent perivascular mesenchymal stem cells.PLoS One. 7: e35577.4.Stockinger, H.et al.(1990) Molecular characterization and functional analysis of the leukocyte surface protein CD31.J Immunol. 145 (11): 3889-97.5.DeLisser, H.M.et al.(1994) Molecular and functional aspects of PECAM-1/CD31.Immunol Today. 15 (10): 490-5.6.Urquhart, P.et al.(2007) Carbon monoxide-releasing molecules modulate leukocyte-endothelial interactions under flow.J Pharmacol Exp Ther. 321 (2): 656-62.7.Reedquist, K.A.et al.(2000) The small GTPase, Rap1, mediates CD31-induced integrin adhesion.J Cell Biol. 148: 1151-8.8.Vernon-Wilson, E.F.et al.(2007) CD31 delays phagocyte membrane repolarization to promote efficient binding of apoptotic cells.J Leukoc Biol. 82: 1278-88.9.Johnston, A.et al.(2005) The anti-inflammatory action of methotrexate is not mediated by lymphocyte apoptosis, but by the suppression of activation and adhesion molecules.Clin Immunol. 114: 154-63.10.Hilbe Wet al.(2003) Immunohistochemical typing of non-small cell lung cancer on cryostat sections: correlation with clinical parameters and prognosis.J Clin Pathol. 56 (10): 736-41.

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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