Human Anti-Adalimumab, clone AbD18655_hIgG1 HCA204P bio-rad,Human Anti-Adalimumab, clone AbD18655_hIgG1

2024-10-22

Human Anti-Adalimumab, clone AbD18655_hIgG1

货号:HCA204P

规格:0.1 mg

价格:5653

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:Adalimumab

物种:其它

宿主:人

抗体亚型:IgG1

克隆号:AbD18655_hIgG1

荧光染料:HRP

产品介绍
Human Anti-Adalimumab, clone AbD18655_hIgG1, is an ultra-high affinity anti-idiotypic antibody that specifically recognizes adalimumab monoclonal antibody and inhibits the binding of adalimumab to its target, TNFα. Clone AbD18655_hIgG1 can be used to measure the levels of adalimumab and biosimilar products using bioanalytical assays. It may also be used to develop and calibrate immune response assays to measure the anti-drug antibody (ADA) response in patient serum.Adalimumab (branded as Humira) is a fully human monoclonal antibody (IgG1/kappa) approved for the treatment of ankylosing spondylitis, Crohn’s disease, psoriasis and several forms of arthritis. The antibody is specific for TNFα, and acts by blocking the activation of TNF receptors by TNFα. This inactivation down-regulates the inflammatory reactions associated with autoimmune diseases.
产品详情
Product FormHuman IgG1 antibody (lambda light chain) selected from the HuCAL® phage display library and expressed in a human cell line. Conjugated to horseradish peroxidase (HRP) - liquid.
PreparationPurified IgG prepared by affinity chromatography on Protein A
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.01% Thiomersal
ImmunogenAdalimumab
AffinityThe monovalent intrinsic affinity of this antibody in an unconjugated format was measured as KD=0.06 nM by real time, label-free molecular interaction analysis on immobilized adalimumab.
Approx. Protein ConcePurityntrationsTotal protein concentration 1.0 mg/ml
AcknowledgementsThis product and/or its use is covered by claims of U.S. patents, and/or pending U.S. and non-U.S. patent applications owned by or under license to Bio-Rad Laboratories, Inc. See bio-rad.com/en-us/trademarks for details.Humira is a registered trademark of Abbott Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application NameVerifiedMin DilutionMax Dilution
ELISA
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
产品推荐
DescriptionProduct CodeApplicationsPack Size
Human anti AdalimumabHCA202E0.1mg

技术参数

产品应用 elisa

产品类型 单克隆抗体

推荐用于 elisa

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