Animal-Free Recombinant Human BMP-4 (E.coli derived)
货号：AF-120-05ET-2,AF-120-05ET-10,AF-120-05ET-50,AF-120-05ET-100,AF-120-05ET-250,AF-120-05ET-500,AF-120-05ET-1000
规格：2μg,10μg,50μg,100μg,250μg,500μg,1mg
价格：791,1778,6257,10437,17606,26157,40319
产品类型：细胞因子添加物
品牌：PeproTech
| 产品详情产品编号：AF-120-05ET产品描述：Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body, and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. PeproTech’sE.coli-derived BMP-4 is a fully active homodimeric protein consisting of two 107 amino acid subunits, which correspond to amino acids 303-408 of the full length BMP-4 precursor, and includes a N-terminal Met residue. The calculated molecular weight of Recombinant Human BMP-4 (E.coli-derived) is 24.2 kDa.Manufactured using all Animal-Free reagents.Source:E.coliSynonyms:Bone Morphogenetic Protein-4, BMP-2B, DVR4AA Sequence (monomer):MKKNKNCRRH SLYVDFSDVG WNDWIVAPPG YQAFYCHGDC PFPLADHLNS TNHAIVQTLV NSVNSSIPKA CCVPTELSAI SMLYLDEYDK VVLKNYQEMV VEGCGCRPurity:≥ 98% by SDS-PAGE gel and HPLC analyses.Biological Activity:Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expectedED50for this effect is 5-10 ng/ml.Calculated Molecular Weight:23.9 kDaAccession Number:P12644Gene ID:652Note:1mg will be provided as 2x500μg.crossreactivity:Human,Mouse,Rat,SalamanderCountry Of Origin:USANot for human use. |
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