Human anti Human HbA1c antibody, clone AbD15792 HCA200 bio-rad,Human anti Human HbA1c antibody, clone AbD15792-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Human anti Human HbA1c antibody, clone AbD15792 HCA200 bio-rad,Human anti Human HbA1c antibody, clone AbD15792

2024-10-22

Human anti Human HbA1c antibody, clone AbD15792

货号：HCA200

规格：0.1 mg

价格：2440

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：HbA1c

物种：其它

宿主：人

抗体亚型：HuCAL Fab monovalent

克隆号：AbD15792

荧光染料：Purified

产品介绍
Human anti Human HbA1c antibody, clone AbD15792recognizes HbA1c, i.e. hemoglobin when glycated at the N-terminal valine of the hemoglobin β chain. It does not bind to non-glycated hemoglobin. Besides binding to the normal glycated hemoglobin, it also recognizes the glycated hemoglobin variants HbD and HbE, but does not recognize the HbS or HbC variants. Elevated HbF cannot be detected due to the absence of the hemoglobin β chain.The measurement of HbA1c levels is used to identify the average plasma glucose concentration. In diabetes mellitus, higher levels of HbA1c have been associated with cardiovascular and other diseases. Levels of more than 6.5% HbA1c (48 mmol/mol) are used as a criterion to diagnose diabetes.
产品详情
Target Species	Human
Product Form	A monovalent human recombinant Fab (lambda light chain) selected from the HuCAL® phage display library, expressed inE. coli.The antibody is tagged with a V5 tag and a double extended Strep-tag at the C-terminus of the antibody heavy chain. This antibody is supplied as a liquid.
Preparation	StrepTactin affinity chromatography
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.01% Thiomersal
Immunogen	The immunogens used in the generation of this antibody were:A glycated peptide, corresponding to N-terminal 9 amino acids of haemoglobin beta chain coupled to carrier proteinsPurified HbA1cAlemtuzumab.
Affinity	The affinity of this antibody, as measured against the immunogen, was measured as KD=7 nM by real time, label-free molecular interaction analysis using HbA1c-BSA and HbA1c-TRF conjugates as immobilized antigen.The affinity of this antibody, as measured against purified HbA1c, was measured as KD=54 nM by real time, label-free molecular interaction analysis using full length HbA1c as immobilized antigen.
Approx. Protein ConcePurityntrations	Total protein concentration 0.5 mg/ml
Acknowledgements	This product and/or its use is covered by claims of U.S. patents, and/or pending U.S. and non-U.S. patent applications owned by or under license to Bio-Rad Laboratories, Inc. See bio-rad.com/en-us/trademarks for details.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
ELISA	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 elisa

产品类型单克隆抗体

推荐用于 elisa

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Human anti Human HbA1c antibody, clone AbD15792 HCA200 bio-rad,Human anti Human HbA1c antibody, clone AbD15792

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