Rabbit anti Human Flt3 Ligand antibody AHP770 bio-rad,Rabbit anti Human Flt3 Ligand antibody

2024-10-22

Rabbit anti Human Flt3 Ligand antibody

货号:AHP770

规格:0.1 mg

价格:4063

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原: Flt3 Ligand

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti Human Flt3 Ligand antibodyrecognizes the ubiquitously expressed human growth factor Flt3-Ligand (Flt3L), a 235aa type I transmembrane glycoprotein which regulates the proliferation of early haematopoietic cells.Flt3L exists in both a membrane-bound and proteolytically cleaved soluble isoform, both of which are biologically active, and initiates cell proliferation/ differentiation signalling in co-operation with other colony stimulating factors (CSFs) and interleukins, by binding to and activating the tyrosine kinase receptor Flt3 (FLT3R), expressed highly by hematopoietic progenitor cells and stem cells.
产品详情
Target SpeciesHuman
Product FormPurified IgG - lyophilized
ImmunogenRecombinant human Flt3-Ligand.
ReconstitutionReconstitute with 0.1ml distilled water. For long term storage the addition of 0.09% sodium azide is recommended. NB. For functional studies do not add azide.
Buffer SolutionPhosphate buffered saline
Approx. Protein ConcentrationsIgG concentration 1.0 mg/ml after reconstitution
Antiserum PreparationAntisera to human Flt3-Ligand were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Preservative StabilisersNone present.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Prior to reconstitution store at -20°C.After reconstitution store at -20°C.This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application NameVerifiedMin DilutionMax Dilution
ELISA0.5ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
DescriptionProduct CodeApplicationsPack Size
Goat anti Rabbit IgG (Fc):BiotinSTAR121BE,WB1mg
Goat anti Rabbit IgG (H/L):HRPSTAR124PC,E,WB1mg
文献
1.Graddis, T.J.et al.(1998) Structure-function analysis of FLT3 ligand-FLT3 receptor interactions using a rapid functional screen.J Biol Chem. 273 (28): 17626-33.2.Wodnar-filipowicz, A.et al.(1996) Flt3 ligand level reflects hematopoietic progenitor cell function in aplastic anemia and chemotherapy-induced bone marrow aplasia.Blood. 88 (12): 4493-9.

技术参数

产品类型 wb;elisa

推荐用于 Polyclonal Antibody

组成成分 wb;elisa

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