Goat anti Human LIVIN (C terminal) antibody AHP648 bio-rad,Goat anti Human LIVIN (C terminal) antibody

2024-10-22

Goat anti Human LIVIN (C terminal) antibody

货号:AHP648

规格:0.1 mg

价格:4463

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原: LIVIN (C terminal)

物种:人

宿主:山羊

抗体亚型:IgG

荧光染料:Alexa Fluor 488

产品介绍
Goat anti Human LIVIN (C terminal) antibodyrecognizes human Baculoviral IAP repeat-containing protein 7, also known as Kidney inhibitor of apoptosis protein, Livin, RING finger protein 50 or Melanoma inhibitor of apoptosis protein, encoded by the BIRC7 gene. Livin is a 298 amino acid, ~30kDa member of the IAP family containing a singleBIRrepeat and a singleRING -type Zinc fingerdomain. Goat anti human Livin antibody, recognizes an epitope within the C-terminal (CT) region of human Livin. Two isoforms of livin are generated by alternative splicing α or isoform 2, and β or isoform 1, the latter carrying a 18 amino acid deletion toward the C-terminal region of the molecule. However, the deletion seen in Livin-β is outside the sequence used as immunogen for this Goat anti human Livin antibody which is expected to recognize both isoforms of the molecule.Livin is upregulated in a number of cancer cell types demonstrating both nuclear and cytoplasmic localization in renal cancer cells whilst equivalent non-cancerous kidneys demonstrate only cytoplasmic staining in restricted cell types (Wageneret al.2007).
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
Antiserum PreparationAntisera to human LIVIN (CT) were raised by repeated immunisations of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Buffer SolutionTRIS buffered saline
Preservative Stabilisers<0.1% Sodium Azide (NaN3)
ImmunogenPeptide sequence C-RAPVRSRVRT corresponding to the C-terminal region of LIVIN (UniProt: Q96CA5).
Approx. Protein ConcentrationsIgG concentration 0.5 mg/ml
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application NameVerifiedMin DilutionMax Dilution
ELISA1/4,000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
DescriptionProduct CodeApplicationsPack Size
Rabbit anti Goat IgG (Fc):FITCSTAR122FF100 Tests
Rabbit anti Goat IgG (Fc):HRPSTAR122PC,E,WB100 Tests

技术参数

产品应用 wb;elisa

产品类型 Polyclonal Antibody

推荐用于 wb;elisa

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