Rabbit anti ZAP 70 (pTyr493) antibody AHP2692 bio-rad,Rabbit anti ZAP 70 (pTyr493) antibody

2024-10-22

Rabbit anti ZAP 70 (pTyr493) antibody

货号:AHP2692

规格:50 µl

价格:3613

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:ZAP 70 (pTyr493)

物种:其它

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti ZAP 70 (pTyr493) antibodyrecognizes ZAP 70, also known as Zeta-chain-associated protein kinase 70 when phosphorylated at tyrosine 493. ZAP70 is a member of the tyrosine kinase family. ZAP 70 plays a key role in the activation of T cells. ZAP 70 is phosphorylated at tyrosine 493 by Lck in response to T cell receptor stimulation (Wanget al.2010). Phosphorylation of ZAP 70 at tyrosine 493 fully activates ZAP 70 leading to phosphorylation of downstream targets of the T cell activation pathway.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
Antiserum PreparationAntiserum to ZAP 70 (pTyr493) was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.02% Sodium Azide50% Glycerol
ImmunogenPhospho specific-peptide corresponding to residues surrounding tyrosine 493 of human ZAP 70
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store at -20℃Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting1/5001/2000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Katzav, S. (2015) Vav1: A Dr. Jekyll and Mr. Hyde protein--good for the hematopoietic system, bad for cancer.Oncotarget. 6 (30): 28731-42.

技术参数

产品应用 wb

产品类型 Polyclonal Antibody

推荐用于 wb

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