Rabbit anti retinoblastoma (pSer780) antibody AHP2676 bio-rad,Rabbit anti retinoblastoma (pSer780) antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rabbit anti retinoblastoma (pSer780) antibody AHP2676 bio-rad,Rabbit anti retinoblastoma (pSer780) antibody

2024-10-22

Rabbit anti retinoblastoma (pSer780) antibody

货号：AHP2676

规格：50 µl

价格：3613

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：retinoblastoma (pSer780)

物种：其它

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti retinoblastoma (pSer780) antibodyrecognizes retinoblastoma gene protein, also known as retinoblastoma-associated protein, p105-Rb, pp110 and Rb, when phosphorylated at serine 780. Retinoblastoma-associated protein is a tumor suppressor protein that plays a key role in G1checkpoint control. In quiescent cells retinoblastoma-associated protein forms a repressor complex by binding to E2F transcription factors. Phosphorylation of retinoblastoma-associated protein results in dissociation from E2F, allowing for cell cycle progression.Retinoblastoma-associated protein is phosphorylated at serine 780 by cyclin-D-cdk4/6 complexes, p38 MAPK kinase and aurora b kinase (Macdonald and Dick 2012).
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Antiserum Preparation	Antiserum to retinoblastoma (pSer780) was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.02% Sodium Azide50% Glycerol
Immunogen	Phospho specific-peptide corresponding to residues surrounding serine 780 of human retinoblastoma
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
Store at -20℃Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√	1/500	1/2000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
Description	Product Code	Applications	Pack Size
Goat anti Rabbit IgG (H/L):HRP	STAR124P	C,E,WB	1mg
Goat anti Rabbit IgG (Fc):Biotin	STAR121B	E,WB	1mg
文献
1.Macdonald, J.I. & Dick, F.A. (2012) Posttranslational modifications of the retinoblastoma tumor suppressor protein as determinants of function.Genes Cancer. 3 (11-12): 619-33.

技术参数

产品应用 wb

产品类型 Polyclonal Antibody

推荐用于 wb

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Rabbit anti retinoblastoma (pSer780) antibody AHP2676 bio-rad,Rabbit anti retinoblastoma (pSer780) antibody

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