Rabbit anti BAD (pSer112) antibody AHP2556 bio-rad,Rabbit anti BAD (pSer112) antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rabbit anti BAD (pSer112) antibody AHP2556 bio-rad,Rabbit anti BAD (pSer112) antibody

2024-10-22

Rabbit anti BAD (pSer112) antibody

货号：AHP2556

规格：50 µl

价格：3570

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：BAD (pSer112)

物种：其它

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti BAD (pSer112) antibodyrecognizes Bcl2-associated agonist of cell death (BAD), also known as Bcl-xL/Bcl-2-associated death promoter, Bcl-2 binding component 6 or Bcl2-L-8, when phosphorylated at serine 112.Similar to the other Bcl-2 protein family members, Bax, Bak, Bid and Bock, BAD has a pro-apoptotic function in the apoptosis signaling cascade.The precise role of BAD in apoptosis signaling depends on BAD’s post-translational modification status. Nonphosphorylated BAD forms heterodimers with the two anti-apoptotic Bcl-2 protein family members, Bcl-xL and Bcl-2 (Zhaet al.1996). The binding of BAD to Bcl-xL promotes apoptosis by inhibiting the apoptosis repressor function of Bcl-xL (Yanget al.1995). Once serine phosphorylated, BAD is unable to heterodimerize with Bcl-xL and interacts with 14-3-3 proteins instead (Masterset al.1995). This binding retains BAD in the cytoplasm and thereby enables Bcl-xL to suppress apoptosis (Zhaet al.1996). Phosphorylation of BAD at serine 112 is stimulated by activated MAPK kinases.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Antiserum Preparation	Antiserum to BAD (pSer112) was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.02% Sodium Azide50% Glycerol
Immunogen	Phospho specific-peptide corresponding to residues surrounding serine 112 of human BAD
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
Store at -20℃Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√	1/500	1/2000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
Description	Product Code	Applications	Pack Size
Goat anti Rabbit IgG (Fc):Biotin	STAR121B	E,WB	1mg
Goat anti Rabbit IgG (H/L):HRP	STAR124P	C,E,WB	1mg

技术参数

产品应用 wb

产品类型 Polyclonal Antibody

推荐用于 wb

© bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：https://gibcohyclone.cn/thread-42218.htm

特别声明：以上内容(如有图片亦包括在内)来源于授权厂家或网络，如有侵权，请联系删除，本平台不提供信息存储服务。

Notice: The content above (including the pictures if any)comes from authorized manufacturers or networks. In case of infringement, please contact to delete it. This platform does not provide information storage services.

产品询价需求提交

Rabbit anti BAD (pSer112) antibody AHP2556 bio-rad,Rabbit anti BAD (pSer112) antibody

相关推荐