Rabbit anti BCR (pTyr177) antibody AHP2559 bio-rad,Rabbit anti BCR (pTyr177) antibody

2024-10-22

Rabbit anti BCR (pTyr177) antibody

货号:AHP2559

规格:50 µl

价格:3570

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:BCR (pTyr177)

物种:其它

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti BCR (pTyr177) antibodyrecognizes breakpoint cluster region protein (BCR), also known as Renal carcinoma antigen NY-REN-26, when phosphorylated at tyrosine 177. The BCR protein is a GTPase activating protein and a serine/threonine kinase. A translocation event between chromosomes 9 and 22 results in the fusion of c-ABL and BCR genes and subsequent expression of the BCR/ABL fusion protein (Hantschel and Superti-Furga, 2004). BCR/ABL is associated with chronic myeloid leukaemia (CM).Phosphorylation of tyrosine 177 of BCR (in the BCR/ABL fusion protein) plays a key role in BCR/ABL mediated myeloproliferative disease (MPD) (Quintás-Cardama and Cortes, 2009).
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
Antiserum PreparationAntiserum to BCR (pTyr177) was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.02% Sodium Azide50% Glycerol
ImmunogenPhospho specific-peptide corresponding to residues surrounding tyrosine 177 of human BCR
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store at -20℃Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting1/5001/2000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
DescriptionProduct CodeApplicationsPack Size
Goat anti Rabbit IgG (Fc):BiotinSTAR121BE,WB1mg
Goat anti Rabbit IgG (H/L):HRPSTAR124PC,E,WB1mg

技术参数

产品类型 wb

推荐用于 Polyclonal Antibody

组成成分 wb

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