Bio-Rad E3 UBIQUITIN-PROTEIN Ligase CBL抗体 AHP2416,Rabbit anti E3 UBIQUITIN-PROTEIN Ligase CBL

2024-10-22

Rabbit anti E3 UBIQUITIN-PROTEIN Ligase CBL

货号:AHP2416

规格:0.1 mg

价格:3213

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原: E3 UBIQUITIN-PROTEIN Ligase CBL

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍

Rabbit anti E3 ubiquitin-protein ligase CBL antibodyrecognizes the Casitas B-lineage lymphoma (CBL) E3 ubiquitin ligase, also known as c-CBL proto-oncogene and ring finger protein 55. As the name implies, the viral form of CBL, v-CBL, has been shown to induce lymphoma and leukemia in mice (de Jonget al.1995).The CBL protein is a RING finger E3-ubiquitin ligase that plays a key role in signal transduction processes through mediating monoubiquitination and thereby endocytosis of receptor tyrosine kinases (Haglundet al.2002,Dikic and Giordano 2003). In addition to this role, CBL has also been reported to act as an adaptor protein as well as a mediator of cell signaling processes by changing the cellular localization of substrates (Liyasovaet al.2015).

产品详情

Target Species

Human

Species Cross-Reactivity

Target Species Cross Reactivity

Mouse √

Rat √

N.B. Antibody reactivity and working conditions may vary between species.

Product Form

Purified IgG - liquid

Preparation

Purified IgG prepared by affinity chromatography

AntiserumPreparation

Antiserum to E3 ubiquitin-protein ligase CBL was raised by repeated immunisation of rabbits with highly purified antigen

Buffer Solution

Phosphate buffered saline

Preservative Stabilisers

0.1% Sodium Azide (NaN3)0.2% Gelatin

Immunogen

Peptide mapping to the carboxy terminal domain of human E3 ubiquitin-protein ligase CBL

Approx. Protein Concentrations

IgG concentration 0.2 mg/ml

Regulatory

For research purposes only

Guarantee

12 months from date of despatch

存储条件

Store at +4℃. DO NOT FREEZE.This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.

应用

Application Name

Verified

Min Dilution

Max Dilution

Western Blotting

    1/200

    4ug/ml

    This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
    • Western Blotting
    • Rabbit anti E3 ubiquitin-protein ligase CBL recogninizes a band of approximately117 kDa when run under reducing conditions

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