Human IL-27 R alpha ELISA Kit ELISA试剂盒,Human IL-27 R alpha ELISA Kit/人IL-27 R alpha ELISA试剂盒

2024-10-24

Human IL-27 R alpha ELISA Kit/人IL-27 R alpha ELISA试剂盒

货号:EH272RB,EH272RBX5,EH272RBX10

规格:96 Tests,5X96 Tests,10X96 tests

价格:6327,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.85 ng/mL

检测范围0.85-200 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameTCCR
Protein aliasesclass I cytokine receptor, Cytokine receptor WSX-1, Cytokine receptor-like 1, IL-27 receptor subunit alpha, IL-27R subunit alpha, IL-27R-alpha, interleukin 27 receptor, alpha, Interleukin-27 receptor subunit alpha, T-cell cytokine receptor type 1, TCCR, Type I T-cell cytokine receptor, ZcytoR1

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesCRL1, IL-27RA, IL27R, IL27RA, TCCR, UNQ296/PRO336, WSX1, zcytor1
Gene ID(Human) 9466
Gene symbolIL27RA
UniProt ID(Human) Q6UWB1
Human IL-27 R alpha quantitates human IL-27 R alpha in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human IL-27 R alpha.人IL-27 R alpha定量检测血清,血浆,上清液中的人IL-27 R alpha。 该检测试剂盒将只识别天然和重组人IL-27 Rα。Target information 靶标信息Upon antigen challenge, T-helper cells differentiate into two functional distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-gamma and lymphotoxin-beta that augment cell mediated immune response while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned. It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1. TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-gamma and Th1-dependent antibody IgG2a. TCCR is predominately expressed in thymus, spleen, lymph notes and peripheral blood leukocytes.抗原攻击后,T辅助细胞分化为两个功能不同的亚群Th1和Th2。 Th1细胞产生IL-2,IFN-γ和淋巴毒素β,从而增强细胞介导的免疫反应,而Th2细胞分泌能够增强体液免疫的IL-4,IL-5和IL-10。 T辅助细胞的功能受细胞因子调节。 最近鉴定并克隆了一种新的细胞因子受体。 它是I型细胞因子受体家族的新成员,并指定为T细胞细胞因子受体和WSX-1的TCCR。 TCCR缺陷的小鼠损害了Th1对蛋白质抗原攻击的反应,包括IFN-γ和Th1依赖性抗体IgG2a水平降低。 TCCR主要在胸腺,脾脏,淋巴液和外周血白细胞中表达。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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