Bio-Rad c-Fos抗体 AHP2411,Rabbit anti c-Fos

2024-10-22

Rabbit anti c-Fos

货号:AHP2411

规格:0.1 mg

价格:2576

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:c-Fos

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍

Rabbit anti c-Fos antibodyrecognizes c-Fos also known as G0/G1 switch regulatory protein 7 (G0S7). The c-Fos transcription factor is encoded by the c-Fos proto-oncogene and dimerizes with c-Jun, JDP and ATF family members to form the AP-1 transcription factor (Eferl and Wagner 2003).c-Fos plays an essential role in mediating cellular signaling responses after cellular stress. The ability of the c-Fos protein to act as a transcription factor is regulated by phosphorylation on selected sites by the kinases p38, ERK, RSK1 and RSK2 (Lopez-Bergamiet al.2011). The protein accumulates in the nucleus, where it acts as a transcription factor upon formation of heterodimers with c-Jun. This binding prevents the nuclear export and subsequent proteosomal degradation of c-Fos (Halazonetiset al.1988).

产品详情

Target Species

Human

Species Cross-Reactivity

Target SpeciesCross Reactivity

Mouse √

Rat √

N.B. Antibody reactivity and working conditions may vary between species.

Product Form

Purified IgG - liquid

Preparation

Purified IgG prepared by affinity chromatography

AntiserumPreparation

Antiserum to c-Fos was raised by repeated immunisation of rabbits with highly purified antigen

Buffer Solution

Phosphate buffered saline

Preservative Stabilisers

0.1% Sodium Azide (NaN3)0.2% Gelatin

Immunogen

Peptide mapping to the amino terminus of human c-Fos

Approx. Protein Concentrations

IgG concentration 0.2 mg/ml

Regulatory

For research purposes only

Guarantee

12 months from date of despatch

存储条件

Store at +4℃. DO NOT FREEZE.This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.

应用

Application Name

Verified

Min Dilution

Max Dilution

Western Blotting

1/200

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
  • Western Blotting
  • Rabbit anti c-Fos recognizes a band of approximately 55 kDa when run under reducing conditions

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技术参数

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产品类型 Polyclonal Antibody

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