Bio-Rad AHP2020 FOXP2,Goat anti Human FOXP2 antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Bio-Rad AHP2020 FOXP2,Goat anti Human FOXP2 antibody

2024-10-22

Goat anti Human FOXP2 antibody

货号：AHP2020

规格：0.1 mg

价格：6095

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原： FOXP2

物种：人

宿主：山羊

抗体亚型：IgG

荧光染料：Purified

产品介绍
Goat anti Human FOXP2 antibodyrecognizes Forkhead box protein P2, also known as FOXP2, CAG repeat protein 44 or Trinucleotide repeat-containing gene 10 protein. FOXP2 is a 715 amino acid ~80 kDa nuclear transcriptional repressor with a role in brain and lung development.Mutations in the FOXP2 gene has been identified Speech-language disorder 1 (SPCH1), a disorder characterized by severe orofacial dyspraxia with speech impairment (Laiet al.2001).Multiple potential isoforms of FOXP2 generated by alternative splicing have been described. Goat anti Human FOXP2 antibody (AHP2020) is expected to recognize the canonical isoform 1 and also isoforms 3 and 9. However the antibody is not expected other isoforms which lack the c-terminal region (UniProt : 015409).
产品详情
Target Species	Human
Species Cross-Reactivity	Target Species	Cross Reactivity
Mammals	Expected from Sequence
N.B. Antibody reactivity and working conditions may vary between species.
Product Form	Purified IgG - liquid
Antiserum Preparation	Antiserum to human FOXP2 (CT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Buffer Solution	TRIS buffered saline
Preservative Stabilisers	0.02% Sodium Azide (NaN3)0.5% Bovine Serum Albumin
Immunogen	Peptide with sequence C-REIEEEPLSEDLE from the C Terminus of FOXP2.
Approx. Protein Concentrations	IgG concentration 0.5 mg/ml
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
Prior to reconstitution store at -20°C.After reconstitution store at -20°C.This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application Name	Verified	Min Dilution	Max Dilution
ELISA	√	1/32000
Western Blotting	√	0.5	1.5ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.Western BlottingAHP2020 detects a band of approximately 80kDa in human cerebellum cell lysates.
数据
Western blotting analysis of human cerebellum lysate (35μg protein in RIPA buffer) probed with Goat anti Human FOXP2 antibody (AHP2020) at 0.5μgml-1. Primary incubation was 1 hour. Signal was detected by chemiluminescence.
文献
1. Vernes, S.C.et al.(2007) High-throughput analysis of promoter occupancy reveals direct neural targets of FOXP2, a gene mutated in speech and language disorders.Am J Hum Genet. 81 (6): 1232-50.2. Vernes, S.C.et al.(2006) Functional genetic analysis of mutations implicated in a human speech and language disorder.Hum Mol Genet. 15 (21): 3154-67.

技术参数

产品应用 E;WB

产品类型 Polyclonal Antibody

推荐用于 E;WB

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Bio-Rad AHP2020 FOXP2,Goat anti Human FOXP2 antibody

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