Bio-Rad AHP1939 EGR1,Rabbit anti EGR1 antibody

2024-10-22

Rabbit anti EGR1 antibody

货号:AHP1939

规格:50 µg

价格:5933

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:EGR1

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti EGR1 antibodyrecognizes human Early Growth Response Protein 1. EGR1 is a ~58 kDa nuclear protein belonging to the EGR family of C2H2-type zinc-finger proteins.EGR1 functions as a transcriptional regulator. The products of target genes it activates are required for differentiation and mitogenesis. Research has also demonstrated that EGR1 expression is elevated in a range of cancers including prostate cancer where EGR1 has been shown to promote the growth of tumor cells.
产品详情

Target Species

Human
Species Cross-ReactivityTarget SpeciesCross Reactivity
BovineExpected from Sequence
ChimpanzeeExpected from Sequence
DogExpected from Sequence
Rhesus MonkeyExpected from Sequence
SheepExpected from Sequence
N.B. Antibody reactivity and working conditions may vary between species.

Product Form

Purified IgG - liquid

Antiserum Preparation

Antisera to Human EGR1 were raised by repeatedimmunisation of rabbits with highly purified antigen. Purified IgG prepared from whole serum by affinity chromatography.

Buffer Solution

Phosphate buffered saline

Preservative Stabilisers

<0.1% Sodium Azide (NaN3)

Immunogen

A synthetic peptide sequence corresponding to amino acid 94 - 108 of human EGR1.
Approx. Protein ConcentrationsIgG concentration 0.5 mg/ml

Regulatory

For research purposes only

Guarantee

12 months from date of despatch
存储条件
Prior to reconstitution store at -20°C.After reconstitution store at -20°C.This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用

Application Name

Verified

Min Dilution

Max Dilution

ELISA
Immunohistology - Paraffin110 ug/ml
Western Blotting
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.Sodium citrate buffer pH 6.0 is recommended for this purpose.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.Histology Positive Control TissueLung small cell carcinoma
数据

Staining of formalin fixed, paraffin embedded human lung small cell carcinoma with Rabbit anti Human EGR1 (AHP1939),
相关试剂
DescriptionProduct CodeApplicationsPack Size
TidyBlot Western Blot Detection Reagent:HRPSTAR209PWB0.5 mL
Antigen Retrieval Buffer, pH8.0BUF025AIHC(P)500 mL
文献
1. Abu El-Asrar, A.M.et al(2011) Expression of high-mobility groups box-1/receptor for advanced glycation end products/osteopontin/early growth response-1 pathway in proliferative vitreoretinal epiretinal membranesMol Vis. 2011 Feb 17;17:508-18.

技术参数

产品应用 E;P*;WB

产品类型 Polyclonal Antibody

推荐用于 E;P*;WB

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