Bio-Rad Mcl-1抗体 AHP2138,Goat anti Human Mcl-1 (C-Terminal)

2024-10-22

Goat anti Human Mcl-1 (C-Terminal)

货号:AHP2138

规格:0.1 mg

价格:5083

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:Mcl-1

物种:人

宿主:山羊

抗体亚型:IgG

荧光染料:Purified

产品介绍

Goat anti Human Mcl-1 antibodyrecognises an epitope within the C-Terminal (CT) region of human Mcl-1, otherwise known as Myeloid cell leukaemia sequence 1, a mitochondrial-associated anti-apoptotic member of the Bcl-2 family, which acts as both an enhancer of cell survival (isoform 1), and promoter of cell death (isoform 2).Mcl-1 is expressed in many different cell lines, and several types of cancer, and blockage of its function, may prove to be a useful therapeutic agent in the treatment of malignancies and inflammatory and infectious diseases.Goat anti Human Mcl-1 antibody is expected to recognise the longer gene product, isoform 1.

产品详情

Target Species

Human

Species Cross-Reactivity

Target Species Cross Reactivity

Dog Expected from Sequence

Rat Expected from Sequence

Bovine Expected from Sequence

Pig Expected from Sequence

Mouse Expected from Sequence

N.B. Antibody reactivity and working conditions may vary between species.

Product Form

Purified IgG - liquid

AntiserumPreparation

Antiserum to human Mcl-1 (CT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.

Buffer Solution

TRIS buffered saline

Preservative Stabilisers

0.02% Sodium Azide (NaN3)0.5% Bovine Serum Albumin

Immunogen

Synthetic peptide sequence C-AGVGAGLAYLIR from the C-Terminal region of Mcl-1 (NP_068779.1).

Approx. Protein Concentrations

IgG concentration 0.5mg/ml

Regulatory

For research purposes only

Guarantee

12 months from date of despatch

存储条件

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

应用

Application Name

Verified

Min Dilution

Max Dilution

ELISA

1/2000

Western Blotting

1.0

3.0ug/ml

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
  • Western Blotting
  • AHP2138 detects a band of approximately 35kDa in human lung and K562 cell lysates.

可用二抗

Description

Product Code

Applications

Pack Size

Rabbit anti Goat IgG (Fc):FITC

STAR122F

F

1 mg

Rabbit anti Goat IgG (Fc):HRP

STAR122P

C E WB

1 mg

文献

1.Cencic, R.et al.(2013) Modifying chemotherapy response by targeted inhibition of eukaryotic initiation factor 4A.Blood Cancer J. 3: e128.

技术参数

产品应用 E; WB

产品类型 Polyclonal Antibody

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