Bio-Rad Clusterin抗体 AHP2129,Goat anti Human Clusterin (C-Terminal)

2024-10-22

Goat anti Human Clusterin (C-Terminal)

货号:AHP2129

规格:0.1 mg

价格:5083

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:Clusterin

物种:人

宿主:山羊

抗体亚型:IgG

荧光染料:Purified

产品介绍

Goat anti Human clusterin antibodyrecognizes an epitope within the C-terminal (CT) region of human clusterin, otherwise known as Apolipoprotein J, a ubiquitously expressed glycoprotein and member of the clusterin family, implicated in apoptosis (programmed cell death), cell-cell adhesion, DNA repair, membrane recycling, spermatogenesis, and the inhibition of complement-mediated cell lysis.Clusterin is a component of the SC5b-9 complex which plays a role in inhibiting the complement cascade, through the prevention of the binding of a C5b-C7 complex to the membrane of the target cell. Clusterin exists as both a pro-apoptotic form localised to the nucleus, and a pro-survival secreted form, and has been detected at elevated levels in Alzheimer’s disease, atherosclerosis, myocardial infarction, and various cancers, including bladder, prostate, and breast tumours.

产品详情

Target Species

Human

Species Cross-Reactivity

Target Species Cross Reactivity

Dog Expected from Sequence

N.B. Antibody reactivity and working conditions may vary between species.

Product Form

Purified IgG - liquid

AntiserumPreparation

Antiserum to human clusterin (CT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.

Buffer Solution

TRIS buffered saline

Preservative Stabilisers

0.02% Sodium Azide (NaN3)0.5% Bovine Serum Albumin

Immunogen

Synthetic peptide sequence C-EKALQEYRKKHREE from the C-Terminal region of clusterin (NP_001822.2; NP_976084.1).

Approx. Protein Concentrations

IgG concentration 0.5mg/ml

Regulatory

For research purposes only

Guarantee

12 months from date of despatch

存储条件

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

应用

Application Name

Verified

Min Dilution

Max Dilution

ELISA

1/32000

Western Blotting

0.3

1.0ug/ml

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
  • Western Blotting
  • AHP2129 detects a band of approximately 35-37kDa in human colon, kidney and prostate cell lysates.

可用二抗

Description

Product Code

Applications

Pack Size

Rabbit anti Goat IgG (Fc):FITC

STAR122F

F

1 mg

Rabbit anti Goat IgG (Fc):HRP

STAR122P

C E WB

1 mg

技术参数

产品应用 E; WB

产品类型 Polyclonal Antibody

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