Rabbit anti Human insulin-likegGrowth factor I antibody ,Rabbit anti Human insulin-likegGrowth factor I antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rabbit anti Human insulin-likegGrowth factor I antibody ,Rabbit anti Human insulin-likegGrowth factor I antibody

2024-10-22

Rabbit anti Human insulin-likegGrowth factor I antibody

货号：AHP1281

规格：0.1 mg

价格：4063

产品类型：免疫组化一抗

品牌：Bio-Rad

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti Human insulin-like Growth factor I antibodyrecognizes human IGF-I (Insulin-like Growth Factor I), a 70 amino acid secreted mitogenic polypeptide and member of the insulin gene family, produced primarily by the liver. IGF-I exhibits both autocrine and paracrine properties and has a widespread effect on cells including those of the bone, cartilage, muscle, nerves, skin, liver and lungs, playing a key role in cell proliferation and growth, inhibition of apoptosis and linked with tumour cell growth.IGF-I signals through binding to the type 1 insulin-like growth factor receptor (IGF-1R) and also to the insulin receptor (IR), resulting in the activation of the AKT signalling pathway. Production of IGF-I is stimulated by growth hormone (GH) and can be hindered by GH insensitivity, deficiency in GH receptors or a malfunction in the post GH receptor signalling pathway.
产品详情
Target Species	Human
Product Form	Purified IgG - lyophilized
Antiserum Preparation	Antisera to human IGF-I were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	None present.
Immunogen	Recombinant human IGF-I
Approx. Protein Concentrations	IgG concentration 1.0mg/ml
Regulatory	For research purposes only
Guarantee	6 months from date of despatch
存储条件
Prior to reconstitution store at -20°C.After reconstitution store at -20°C.This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√	0.1	0.2ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
Description	Product Code	Applications	Pack Size
Goat anti Rabbit IgG (Fc):Biotin	STAR121B	E,WB	1mg
Goat anti Rabbit IgG (H/L):HRP	STAR124P	C,E,WB	1mg
文献
1.Singer, C.F.et al.(2004) Insulin-like growth factor (IGF)-I and IGF-II serum concentrations in patients with benign and malignant breast lesions: free IGF-II is correlated with breast cancer size.Clin Cancer Res. 10 (12 Pt 1): 4003-9.

技术参数

产品应用 wb；elisa

产品类型 Polyclonal Antibody

推荐用于 wb；elisa

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Rabbit anti Human insulin-likegGrowth factor I antibody ,Rabbit anti Human insulin-likegGrowth factor I antibody

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