Bio-Rad AHP1343 5-HT7 receptor,Rabbit anti Human 5-HT7 receptor antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Bio-Rad AHP1343 5-HT7 receptor,Rabbit anti Human 5-HT7 receptor antibody

2024-10-22

Rabbit anti Human 5-HT7 receptor antibody

货号：AHP1343

规格：50ug

价格：7310

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原： 5-HT7 receptor

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti Human 5-HT7 receptor antibodyrecognizes the C-terminal region of the serotonin (5-hydroxytryptamine, 5-HT) receptor 5-HT7, which belongs to the G-protein coupled receptor superfamily. Serotonin is a neurotransmitter and vasoactive amine which is thought to play a role in various cognitive and behavioural functions including pain, appetite, mood and sleep.Signalling through 5-HT7has several effects, including regulation of the circadian rhythm and mediation of smooth-muscle relaxation in the vasculature and gastrointestinal tract. Signalling though 5-HT7has also been shown to contribute to early T-cell activation.5-HT7has been implicated in depression, autism, and other neuropsychiatric disorders.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Antiserum Preparation	Antisera to 5-HT7 receptor (CT) were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.1% Sodium Azide (NaN₃)
Approx. Protein Concentrations	IgG concentration 1.0 mg/ml
Immunogen	Synthetic peptide corresponding to the C-terminal regoin of human 5-HT7 receptor, conjugated to Keyhole Limpet Hemocyanin (KLH).
Regulatory	IgG concentration 1.0 mg/ml
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Immunohistology - Paraffin¹	√		10ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage. ¹This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.Sodium citrate buffer pH 6.0 is recommended for this purpose.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls. Histology Positive Control Tissue Brain, cerebellum
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数据
Staining of formalin fixed, paraffin embedded human cerebellum with Rabbit anti Human 5-HT7 receptor (AHP1343)
文献
References for 5-HT7 Receptor antibody1. Kobe, F.et al.(2012) 5-HT7R/G12 Signaling Regulates Neuronal Morphology and Function in an Age-Dependent Manner.J Neurosci. 32: 2915-30.2. Renner, U.et al.(2012) Heterodimerization of serotonin receptors 5-HT1A and 5-HT7 differentially regulates receptor signalling and trafficking.J Cell Sci. 125 (Pt 10): 2486-99.Further Reading1. León-Ponte, M.et al.(2007) Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptor.Blood. 109 (8): 3139-46.

技术参数

产品应用 IHC(P)*

产品类型 Polyclonal Antibody

推荐用于 IHC(P)*

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Bio-Rad AHP1343 5-HT7 receptor,Rabbit anti Human 5-HT7 receptor antibody

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