Bio-Rad AHP1184 SUMO-1,Rabbit anti Human SUMO-1 antibody

2024-10-22

Rabbit anti Human SUMO-1 antibody

货号:AHP1184

规格:0.1 mg

价格:4990

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:SUMO-1

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti Human SUMO-1 antibodyrecognizes the N-terminal (NT) region of small ubiquitin-related modifier-1 (SUMO-1). SUMO-1 is an ~11 kDa protein which structurally related to ubiquitin, and is added to proteins as a form of post-translational modification known as sumoylation. Sumoylation can be cell cycle regulated, stimulated upon stress or induced by DNA damage, and binding elicits individual effects for each protein. Effects include changes to protein stability, nuclear-cytosolic transport, and transcriptional regulation (mostly transcriptional repression).Alternate transcriptional splice variants encoding different isoforms have been characterized.
产品详情

Target Species

Human

Product Form

Purified IgG - liquid

Antiserum Preparation

Antisera to human SUMO-1 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.

Buffer Solution

Phosphate buffered saline

Preservative Stabilisers

0.02%Sodium Azide

Approx. Protein Concentrations

IgG concentration 1.0mg/ml

Immunogen

14 amino acid peptide sequence near the amino terminus of human SUMO-1.

Regulatory

For research purposes only

Guarantee

12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用

Application Name

Verified

Min Dilution

Max Dilution

Immunohistology - Frozen

Western Blotting

0.51.0ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.

Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
  • Western Blotting
  • AHP1184 detects a band of approximately 15kDa in HL-60 cell lysates.
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文献

1. Melchior, F. & Hengst, L. (2002) SUMO-1 and p53.Cell Cycle. 1 (4): 245-9.2. Verger, A.et al.(2003) Modification with SUMO. A role in transcriptional regulation.EMBO Rep. 4 (2): 137-42.

技术参数

产品应用 IHC(F);WB

产品类型 Polyclonal Antibody

推荐用于 IHC(F);WB

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