Bio-Rad AHP1093 Vitamin D Receptor,Goat anti Human Vitamin D Receptor antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Bio-Rad AHP1093 Vitamin D Receptor,Goat anti Human Vitamin D Receptor antibody

2024-10-22

Goat anti Human Vitamin D Receptor antibody

货号：AHP1093

规格：0.1 mg

价格：5083

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：Vitamin D Receptor

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Goat anti Human Vitamin D Receptor antibodyrecognises human vitamin D nuclear hormone receptor (VDR) a ~48 kDa member of the trans-acting transcriptional regulatory factors. On binding vitamin D, VDR regulates the expression of hormone sensitive genes. The main downstream target of VDR is involved in bone mineral metabolism although VDR is also involved in immune response and cancer metabolic pathways. VDR also acts as a receptor for secondary bile acid lithocholic acid. Additionally, signalling and oncogenic activity of beta-catenin signalling has been shown to be repressed by VDR (Shahet al.2006).
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Antiserum Preparation	Antisera to human Vitamin D receptor were raised by repeated immunisations of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution	TRIS buffered saline
Preservative Stabilisers	0.02%Sodium Azide 0.5%Bovine Serum Albumin
Approx. Protein Concentrations	IgG concentration 0.5 mg/ml
Immunogen	Peptide sequence CGNQDYKYRVSD corresponding to the internal region of Vitamin D receptor (NP_000367.1).
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
ELISA	√		1/16,000
Western Blotting	√	0.3	1.0ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage. Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. Western Blotting AHP1093 detects a band of approximately 40-45kDa in human brain cell lysates. A minimum incubation time of 1 hour is recommended with this antibody.
二抗相关产品
Description	Product Code	Applications	Pack Size
Rabbit anti Goat IgG (Fc):FITC	STAR122F	Flow	1 mg
Rabbit anti Goat IgG (Fc):HRP	STAR122P	C;E;WB	1 mg
数据
Western blotting analysis of Human Brain lysate (35μg protein in RIPA buffer) using Goat anti Human vitamin D receptor antibody (AHP1093) at 0.3μgml-1. Primary incubation was 1 hour. Signal was detected by chemiluminescence.
文献
1. Cheng, H.T.et al.(2006) Functional role of VDR in the activation of p27Kip1 by the VDR/Sp1 complex.J Cell Biochem. 98 (6): 1450-6.

技术参数

产品应用 ELISA;WB

产品类型 Polyclonal Antibody

推荐用于 ELISA;WB

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Bio-Rad AHP1093 Vitamin D Receptor,Goat anti Human Vitamin D Receptor antibody

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