Bio-Rad AHP1065 Urokinase,Goat anti Human Urokinase antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Bio-Rad AHP1065 Urokinase,Goat anti Human Urokinase antibody

2024-10-22

Goat anti Human Urokinase antibody

货号：AHP1065

规格：0.1 mg

价格：4463

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：Urokinase

物种：人

宿主：山羊

抗体亚型：IgG

荧光染料：Purified

产品介绍
Goat anti Human Urokinase antibodydetects an epitope within the C-terminal of urokinase, a potent ~50 kDa serine protease also known as urokinase plasminogen activator (uPA). uPA cleaves and activates plasminogen to form plasmin and is involved in extracellular cellular matrix degradation and cell signalling. uPA and its receptor are involved in the pathogenesis of inflammation and immunity.A specific polymorphism in the gene encoding uPA may be associated with late-onset Alzheimer's disease (Ertekin-Taneret al.2005). The levels of uPA, uPAR and its soluble fragments have also been found to be increased in tissues, plasma and other body fluids of cancer patients and to be markers of cancer development and metastasis (Kimet al.2016).
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Antiserum Preparation	Antisera to Urokinase were raised by repeated immunisations of goat with highly purified antigen. Purified IgG prepared by affinity chromatography.
Buffer Solution	TRIS buffered saline
Preservative Stabilisers	0.02%Sodium Azide (NaN₃) 0.5%Bovine Serum Albumin
Approx. Protein Concentrations	IgG concentration 0.5mg/ml
Immunogen	Peptide with sequence C-HFLPWIRSHTKEEN from the C-terminal of the Urokinase sequence.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
ELISA	√		1/8000
Western Blotting	√	0.3	1.0ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls. Western Blotting AHP1065 detects a band of approximately 48kDa in KEH 293 cell lysates.
二抗相关产品
Description	Product Code	Applications	Pack Size
Rabbit anti Goat IgG (Fc):FITC	STAR122F	Flow	1 mg
Rabbit anti Goat IgG (Fc):HRP	STAR122P	C;E;WB	1 mg
数据
Immunohistochemical staining of human placenta with Goat anti Human urokinase antibody (AHP1065) following heat intuced antigen retrieval in citrate buffer pH6.0
文献
1. Mondino, A. & Blasi, F. (2004) uPA and uPAR in fibrinolysis, immunity and pathology.Trends Immunol. 25 (8): 450-5.2. Danø, K.et al.(2005) Plasminogen activation and cancer.Thromb Haemost. 93 (4): 676-81.

技术参数

产品应用 ELISA;WB

产品类型 Polyclonal Antibody

推荐用于 ELISA;WB

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Bio-Rad AHP1065 Urokinase,Goat anti Human Urokinase antibody

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