Bio-Rad PAI-1抗体 AHP1617,Rabbit anti Human PAI-1-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Bio-Rad PAI-1抗体 AHP1617,Rabbit anti Human PAI-1

2024-10-22

Rabbit anti Human PAI-1

货号：AHP1617

规格：0.1 mg

价格：4063

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：PAI-1

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti Human PAI-1 antibodyrecognises human PAI-1, also known as plasminogen activator inhibitor-1 or SERPINE1. PAI-1 is a ~45 kDa serine protease inhibitor and member of the serpin family, which acts as the primary inhibitor of tissue plasminogen activator (tPA) and urokinase plasminogen activator (uPA), and hence fibrinolysis.Mutations of the SERPINE1 gene are associated with Plasminogen activator inhibitor-1 deficiency (PAI-1D), a condition characterized by episodes of severe hemorrhage (Saeset al.2019). Heterozygous carriers of the mutation do not display the same phenotype, instead demonstrate longer teleomere length, lower incidence of diabetes and increased longevity (Khanet al.2017).Increased levels of PAI-1 are associated with diabetes, cardiovascular disease and an increased occurrence of thrombosis in obesity, and can be induced by obesity related factors including insulin, glucose and very-low-density lipoprotein (Altalhiet al.2021).
产品详情
Target Species	Human
Product Form	Purified IgG - lyophilized
Reconstitution	Reconstitute with 0.1ml distilled water. For long term storage the addition of 0.09% sodium azide is recommended.
AntiserumPreparation	Antiserum to human PAI-1 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	None present
Carrier Free	Yes
Immunogen	Recombinant human PAI-1
Approx. Protein Concentrations	IgG concentration 1.0mg/ml
Regulatory	For research purposes only
Guarantee	6 months from date of despatch
存储条件
Prior to reconstitution store at -20°C.After reconstitution store at -20°C.This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application Name	Verified	Min Dilution	Max Dilution
ELISA	√	0.5	2.0ug/ml
Immunohistology -Paraffin¹	√
Western Blotting	√	0.1	0.2ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.¹This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
可用二抗
Description	Product Code	Applications	Pack Size
Goat anti Rabbit IgG (Fc):Biotin	STAR121B	E WB	1 mg
Goat anti Rabbit IgG (Fc):FITC	STAR121F	F	1 mg
Goat anti Rabbit IgG (Fc):HRP	STAR121P	E WB	1 mg
Goat anti Rabbit IgG (H/L):HRP	STAR124P	C E WB	1 mg
Sheep anti Rabbit IgG:FITC	STAR34B	C F	1 mg
Sheep anti Rabbit IgG:RPE	STAR35A	F	1 ml
相关产品
Description	Product Code	Applications	Pack Size
Antigen Retrieval Buffer, pH8.0	BUF025A	P	500 ml
TidyBlot Western Blot Detection Reagent:HRP	STAR209P	WB*	0.5 ml

技术参数

产品应用 E ;P*; WB

产品类型 Polyclonal Antibody

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Bio-Rad PAI-1抗体 AHP1617,Rabbit anti Human PAI-1

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