Bio-Rad RIP2抗体 AHP1590,Rabbit anti RIP2 (N-Terminal)

2024-10-22

Rabbit anti RIP2 (N-Terminal)

货号:AHP1590

规格:0.1 mg

价格:5440

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:RIP2

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍

Rabbit anti Human RIP2 antibodyrecognizes Human Receptor-interacting serine/threonine-protein kinase 2, also known as RIP2, RIPK2, RIP-like-interacting CLARP kinase or CARD-containing interleukin-1 beta-converting enzyme-associated kinase. RIP2 is a 403 amino acid ~60 kDa cytoplasmic protein belonging to the protein kinase superfamily.RIP2 is a kinase that regulates TNF and Fas induced-apoptosis and is involved in the generation of the pro-inflammatory cytokine IL-1beta.Over expression of RIP2 has been shown to induce apoptosis, and the activation of NF-Kappa-B and JNK. RIP2 is widely expressed in a range of human tissues.

产品详情

Target Species

Human

Species Cross-Reactivity

Target SpeciesCross Reactivity

Rat √

Mouse √

N.B. Antibody reactivity and working conditions may vary between species.

Product Form

Purified IgG - liquid

AntiserumPreparation

Antiserum to human RIP2 (NT) was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.

Buffer Solution

Phosphate buffered saline

Preservative Stabilisers

0.02% Sodium Azide (NaN3)

Immunogen

A peptide corresponding to amino acids near the amino terminus of human RIP2.

Approx. Protein Concentrations

IgG concentration 1 mg/ml

Regulatory

For research purposes only

Guarantee

12 months from date of despatch

存储条件

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

应用

Application Name

Verified

Min Dilution

Max Dilution

Immunohistology - Frozen

10ug/ml

Western Blotting

0.5

1.0ug/ml

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.Histology Positive Control TissuePlacentaWestern BlottingRabbit anti Human RIP2 detects a band of approximately 60kDa in A431 cell lysates.

可用二抗

Description

Product Code

Applications

Pack Size

Goat anti Rabbit IgG (Fc):Biotin

STAR121B

E WB

1 mg

Goat anti Rabbit IgG (Fc):FITC

STAR121F

F

1 mg

Goat anti Rabbit IgG (Fc):HRP

STAR121P

E WB

1 mg

Goat anti Rabbit IgG (H/L):HRP

STAR124P

C E WB

1 mg

Sheep anti Rabbit IgG:FITC

STAR34B

C F

1 mg

Sheep anti Rabbit IgG:RPE

STAR35A

F

1 ml

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Product Code

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Pack Size

TidyBlot Western Blot Detection Reagent:HRP

STAR209P

WB*

0.5 ml

文献

1.Inohara N.,et al(1998) RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95-mediated apoptosis.J Biol Chem. 273:12296-300.2.McCarthy J.V.,et al(1998) RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase.J Biol Chem. 273:16968-75.3.Thome M.,et al(1998) Identification of CARDIAK, a RIP-like kinase that associates with caspase-1.Curr Biol. 8:885-8.

技术参数

产品应用 C ;WB

产品类型 Polyclonal Antibody

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