Mouse anti Desmoplakin 1/2 antibody, clone DP-2.15 bio-rad,Mouse anti Desmoplakin 1/2 antibody, clone DP-2.15-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Mouse anti Desmoplakin 1/2 antibody, clone DP-2.15 bio-rad,Mouse anti Desmoplakin 1/2 antibody, clone DP-2.15

2024-10-22

Mouse anti Desmoplakin 1/2 antibody, clone DP-2.15

货号：2722-5204

规格：50 µg

价格：3587

产品类型：免疫组化一抗

品牌：Bio-Rad

物种：其它

宿主：小鼠

抗体亚型：IgG1

荧光染料：Purified

产品介绍
Mouse anti Desmoplakin 1/2 antibody, clone DP-2.15recognizes both desmoplakin 1 and 2 from stratified epithelia, simple epithelia including glands, urothelium, thymic reticular epithelium, hepatocytes, intercalated disks of myocardium and arachnoid cells of meninges. Mouse anti Desmoplakin 1/2 antibody, clone DP-2.15 can be used for the detection of primary and metastatic carcinomas.Mouse anti Desmoplakin 1/2 antibody, clone DP-2.15 recognizes the N terminus of the rod domain of desmoplakin (Bornslaegeret al.1996).
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein A
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	<0.1% Sodium Azide (NaN3)
Immunoge	Native bovine desmoplakin 1 and 2 purified from bovine snout desmosomes.
Approx. Protein Concentrations	IgG concentration 1mg/ml
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Immunofluorescence	√
Immunohistology - Frozen	√
Western Blotting	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
Description	Product Code	Applications	Pack Size
Goat anti Mouse IgG (H/L):FITC (Multi Species Adsorbed)	STAR117F	F	0.5mg
Goat anti Mouse IgG (H/L):Alk. Phos. (Multi Species Adsorbed)	STAR117A	E,WB	0.5mg
文献
1.Cowin, P.et al.(1985) The complement of desmosomal plaque proteins in different cell types.J Cell Biol. 101 (4): 1442-54.2.Jheon, A.H.et al.(2011) PERP regulates enamel formation via effects on cell-cell adhesion and gene expression.J Cell Sci. 124: 745-54.3.Bornslaeger, E.A.et al. (1996) Breaking the connection: displacement of the desmosomal plaque protein desmoplakin from cell-cell interfaces disrupts anchorage of intermediate filament bundles and alters intercellular junction assembly.J. Cell. Biol. 134: 985-1001.4.Park, D.S.et al.(2015) Genetically engineered SCN5A mutant pig hearts exhibit conduction defects and arrhythmias.J Clin Invest. 125 (1): 403-12.5.DeQuach JAet al.(2010) Simple and high yielding method for preparing tissue specific extracellular matrix coatings for cell culture.PLoS One. 5 (9): e13039.6.Basheer, W.A.et al.(2015) Cardiomyocyte-specific overexpression of the ubiquitin ligase Wwp1 contributes to reduction in Connexin 43 and arrhythmogenesis.J Mol Cell Cardiol. 88: 1-13.7.Yung, H.W.et al.(2016) Placental endoplasmic reticulum stress in gestational diabetes: the potential for therapeutic intervention with chemical chaperones and antioxidants.Diabetologia. 59 (10): 2240-50.8.Chkourko, H.S.et al.(2012) Remodeling of mechanical junctions and of microtubule-associated proteins accompany cardiac connexin43 lateralization.Heart Rhythm. 9 (7): 1133-1140.e6.

技术参数

产品应用 WB

产品类型 Monoclonal Antibody

推荐用于 WB

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Mouse anti Desmoplakin 1/2 antibody, clone DP-2.15 bio-rad,Mouse anti Desmoplakin 1/2 antibody, clone DP-2.15

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