PeproTech 120-22 细胞因子人 GDF-3,Recombinant Human GDF-3-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

PeproTech 120-22 细胞因子人 GDF-3,Recombinant Human GDF-3

2024-10-23

Recombinant Human GDF-3

货号：120-22-100,120-22-1000,120-22-20,120-22-250,120-22-5,120-22-500

规格：100ug,1mg,20ug,250ug,5ug,500ug

价格：9171,36743,1568,16052,643,23843

产品类型：细胞因子添加物

品牌：PeproTech

产品描述：GDF-3 is a member of the TGF-β superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF-β family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia that characterizes Type 2 diabetes. Recombinant Human GDF-3 is a 26.0 kDa non-disulfide-linked homodimer containing two 114 amino acid polypeptide chains.来源:E.coli别名:Growth/Differentiation Factor-3, Vgr-2, UNQ2222/PRO248氨基酸序列:AAIPVPKLSC KNLCHRHQLF INFRDLGWHK WIIAPKGFMA NYCHGECPFS LTISLNSSNY AFMQALMHAV DPEIPQAVCI PTKLSPISML YQDNNDNVIL RHYEDMVVDE CGCG纯度:≥98% by SDS-PAGE gel and HPLC analyses.生物活性:Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells. TheED50for this effect is 100-150 ng/ml.Calculated Molecular Weight:26 kDaAccession Number:Q9NR23Gene ID:9573交叉反应:Frog,Mouse

product.subtitle.recentcitations
第一作者	Levine, A J
标题	GDF3 is a BMP inhibitor that can activate Nodal signaling only at very high doses.Levine, A J
文献引用	Developmental Biology; 325(1) pg43-8
PubMed Id	18823971

技术参数

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PeproTech 120-22 细胞因子人 GDF-3,Recombinant Human GDF-3