PeproTech 100-00AB   细胞因子 人 PDGF-AB,Recombinant Human IL-13

2024-10-23

Recombinant Human IL-13

货号:200-13-10,200-13-100,200-13-1000,200-13-2,200-13-250,200-13-50,200-13-500

规格:10ug,100ug,1mg,2ug,250ug,50ug,500ug

价格:1418,11069,44326,582,19355,6634,28757

产品类型:细胞因子添加物

品牌:PeproTech

产品描述:IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching, resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 are cross-species reactive. Recombinant Human IL-13 is a 12.6 kDa protein consisting of 115 amino acid residues.来源:E.coli别名:NC30 (Human), P600 (Murine)氨基酸序列:MSPGPVPPST ALRELIEELV NITQNQKAPL CNGSMVWSIN LTAGMYCAAL ESLINVSGCS AIEKTQRMLS GFCPHKVSAG QFSSLHVRDT KIEVAQFVKD LLLHLKKLFR EGRFN纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:TheED50as determined by the dose-dependent proliferation of TF-1 cells was ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106units/mg.Calculated Molecular Weight:12.6 kDaAccession Number:P35225Gene ID:3596交叉反应:Bacteria,Human,Human + Mouse,Monkey,Mouse,Pig原产国:USA

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