Recombinant Murine IL-6
货号：216-16-10,216-16-100,216-16-1000,216-16-2,216-16-250,216-16-50,216-16-500
规格：10ug,100ug,1mg,2ug,250ug,50ug,500ug
价格：1418,6379,25574,582,11161,3831,16588
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R α and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant Murine IL-6 is a 21.7 kDa protein containing 188 amino acid residues.来源:E.coli别名:26 kDa protein, IFN-b2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2氨基酸序列:MFPTSQVRRG DFTEDTTPNR PVYTTSQVGG LITHVLWEIV EMRKELCNGN SDCMNNDDAL AENNLKLPEI QRNDGCYQTG YNQEICLLKI SSGLLEYHSY LEYMKNNLKD NKKDKARVLQ RDTETLIHIF NQEVKDLHKI VLPTPISNAL LTDKLESQKE WLRTKTIQFI LKSLEEFLKV TLRSTRQT纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:TheED50as determined by the dose-dependent stimulation of the proliferation of IL-6-dependent murine 7TD1 cells is≤ 0.02 ng/ml, corresponding to a specific activity of≥ 5 x 107units/mg.Calculated Molecular Weight:21.7 kDaAccession Number:P08505Gene ID:16193交叉反应：Human,Human + Hamster,Monkey,Mouse,Mouse + Bacteria,Mouse + Virus,Rat,Trout原产国:USA |
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