Recombinant Murine SCF
货号：250-03-10,250-03-100,250-03-1000,250-03-2,250-03-250,250-03-50,250-03-500
规格：10ug,100ug,1mg,2ug,250ug,50ug,500ug
价格：1560,5621,22505,640,9835,3376,14601
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：SCF is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation and differentiation of hematopoietic cells committed to the melanocyte and germ cell lineages. Human SCF manifests low activity on murine cells, while murine and rat SCF are fully active on human cells. The human SCF gene encodes for a 273 amino acid transmembrane protein, which contains a 25 amino acid N-terminal signal sequence, a 189 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 36 amino acid cytoplasmic domain. The secreted soluble form of SCF is generated by proteolytic processing of the membrane anchored precursor. Recombinant Murine SCF is an 18.3 kDa polypeptide containing 165 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF.来源:E.coli别名:Stem Cell Factor, c-Kit Ligand, Mast Cell Growth Factor (MGF), Steel Factor氨基酸序列:MKEICGNPVT DNVKDITKLV ANLPNDYMIT LNYVAGMDVL PSHCWLRDMV IQLSLSLTTL LDKFSNISEG LSNYSIIDKL GKIVDDLVLC MEENAPKNIK ESPKRPETRS FTPEEFFSIF NRSIDAFKDF MVASDTSDCV LSSTLGPEKD SRVSVTKPFM LPPVA纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:TheED50as determined by the dose-dependent stimulation of the proliferation of the human TF-1 cells is≤ 10 ng/ml, corresponding to a specific activity of≥ 1 x 105units/mg.Calculated Molecular Weight:18.3 kDaAccession Number:P20826Gene ID:17311交叉反应：Human,Human + Hamster,Monkey,Mouse,Mouse + Parasite,Mouse + Virus,Rat原产国:USA |
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