Recombinant Human LIF
货号：300-05-100,300-05-1000,300-05-25,300-05-250,300-05-5,300-05-50,300-05-500
规格：100ug,1mg,25ug,250ug,5ug,50ug,500ug
价格：5959,23867,1418,10425,582,3571,15483
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：LIF is a pleiotrophic factor produced by multiple cell types, including T cells, myelomonocytic lineages, fibroblasts, liver, heart and melanoma. LIF promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Other activities include the stimulation of acute phase protein synthesis by hepatocytes, stimulation of differentiation of cholinergic nerves, and suppression of adipogenesis by inhibiting the lipoprotein lipase in adipocytes. While human LIF is active on mouse cells and is widely used in the maintenance of murine ESC to prevent spontaneous differentiation, mouse LIF is not active on human cells due to its inability to bind to the human LIF receptor. Recombinant Human LIF is a 19.7 kDa protein containing 180 amino acid residues, including three disulfide bonds.来源:E.coli别名:Leukemia Inhibitory Factor, Differentiation-stimulating factor, D factor, Melanoma-derived LPL inhibitor (MLPLI), Interleukin 6 family cytokine氨基酸序列:SPLPITPVNA TCAIRHPCHN NLMNQIRSQL AQLNGSANAL FILYYTAQGE PFPNNLDKLC GPNVTDFPPF HANGTEKAKL VELYRIVVYL GTSLGNITRD QKILNPSALS LHSKLNATAD ILRGLLSNVL CRLCSKYHVG HVDVTYGPDT SGKDVFQKKK LGCQLLGKYK QIIAVLAQAF纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:Determined by its ability to stimulate the proliferation of human TF-1 cells. The expectedED50is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107units/mg.Calculated Molecular Weight:19.7 kDaAccession Number:P15018Gene ID:3976交叉反应:Human,Mouse,Rat原产地:USA仅用于科研，不能用于临床和诊断。 |
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