Recombinant Human Oncostatin M (227 a.a.)
货号：300-10-10,300-10-100,300-10-1000,300-10-2,300-10-250,300-10-50,300-10-500
规格：10ug,100ug,1mg,2ug,250ug,50ug,500ug
价格：1418,11069,44326,582,19355,6634,28757
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi’s sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi’s sarcoma cells, but inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptors in hepatoma cells. OSM shares several structural and functional characteristics with LIF, IL-6, and CNTF. Human OSM is active on murine cells. Recombinant Human Oncostatin M is a 25.7 kDa protein, containing 227 amino acid residues (full length precursor).来源:E.coli别名:OSM氨基酸序列:AAIGSCSKEY RVLLGQLQKQ TDLMQDTSRL LDPYIRIQGL DVPKLREHCR ERPGAFPSEE TLRGLGRRGF LQTLNATLGC VLHRLADLEQ RLPKAQDLER SGLNIEDLEK LQMARPNILG LRNNIYCMAQ LLDNSDTAEP TKAGRGASQP PTPTPASDAF QRKLEGCRFL HGYHRFMHSV GRVFSKWGES PNRSRRHSPH QALRKGVRRT RPSRKGKRLM TRGQLPR纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:TheED50as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 2 ng/ml, corresponding to a specific activity of ≥ 5 x 105units/mg.Calculated Molecular Weight:25.7 kDaAccession Number:P13725Gene ID:5008交叉反应:Dog,Human,Human + Mouse,Monkey,Mouse,Pig,Rat原产地:USA仅用于科研，不能用于临床和诊断。 |
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