Animal-Free Recombinant Human BMP-13/CDMP-2
货号:AF-120-04-10,AF-120-04-50,AF-120-04-100,AF-120-04-250,AF-120-04-500,AF-120-04-1000
规格:10µg,50µg,100µg,250µg,500µg,1mg
价格:795,1787,4020,6785,10081,15545
产品类型:细胞因子添加物
品牌:PeproTech
产品详情产品编号:AF-120-04产品描述:BMP-13 is expressed in hypertrophic chondrocytes during embryonic development of long bones. Continued postnatal expression of BMP-13 in articular cartilage suggests that it plays a regulatory role in the growth and maintenance of articular cartilage. Adenovirus-mediated BMP-13 gene transfer to rabbit bone marrow stem cells have been reported to augment periosteal repair of osteochondral defects. The functional form of BMP-13/CDMP-2 is a disulfide-linked homodimer of two 120 amino-acid polypeptide chains. This 27.5 kDa protein is obtained by proteolytic processing of a biologically inactive precursor protein of 97.7kDa. Recombinant Human BMP-13/CDMP-2 is a 27.0 kDa homodimeric disulfide-linked protein consisting of two 120 amino acid polypeptide chains.Manufactured using all Animal-Free reagents.Source:E.coliSynonyms:Bone Morphogenetic Protein-13, GDF-6, Cartilage-Derived Morphogenetic Protein-2 (CDMP-2)AA Sequence (monomer):TAFASRHGKR HGKKSRLRCS KKPLHVNFKE LGWDDWIIAP LEYEAYHCEG VCDFPLRSHL EPTNHAIIQT LMNSMDPGST PPSCCVPTKL TPISILYIDA GNNVVYKQYE DMVVESCGCRPurity:≥ 95% by SDS-PAGE gel and HPLC analyses.Calculated Molecular Weight:27 kDaBiological Activity:Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expectedED50for this effect is 2.0-3.0 µg/mlAccession Number:Q6KF10Gene ID:392255Country Of Origin:USANot for human use. |
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