NGFR Monoclonal Antibody (ME20.4)/NGFR单抗
货号:MA1-20167
规格:50 µL
价格:5548
产品类型:免疫组化一抗
品牌:Thermo Fisher
抗原:Human melanoma cell line, WM245.
物种:人
宿主:小鼠
抗体亚型:其它
克隆号:ME20.4
荧光染料:其它
类型: | 一抗 | 同型对照: | IgG1 |
浓度: | 0.1 mg/mL | 用法: | 1:1,000(IHC(P));Assay-dependent(ICC);Assay-dependent(IF);Assay-dependent(WB) |
产品详细信息Recommended positive controls: human tongue.This antibody does not cross-react with mouse, rat, or chicken p75 NGF receptors.Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.靶标信息Neurotrophic factors control the survival, differentiation and maintenance of neurons in the peripheral and central nervous systems, and of other neural crest-derived cell types. Developing sympathetic neurons are absolutely dependent upon nerve growth factor (NGF) during the period of target competition in vivo. Antibodies reacting specifically with NGFR p75 are useful tools in the detection and characterization of NGFR p75, to enhance our understanding of a wide range of phenomena in the development, plasticity and repair of the nervous system.
数据 |
NGFR Antibody (MA1-20167)Stem cells international 2012 -Figure 3 Series of confocal photographs showing that freshly isolated porcine BM-MNCs do not express Schwann cell markers in neurobasal media. The cells were found to be negative staining for the Schwann cell markers p75(NGF), GFAP, O4, and S100 (a, b, c, d). Nuclei (blue) are stained with DAPI.NGFR Antibody (MA1-20167)Stem cells international 2012 -Figure 5 Confocal photographs showing that BM-MNCs cultured in neurobasal media supplemented with NRG1-III express the p75(NGF) receptor. The addition of 10 nM NRG1-III for 48-hrs to 6-day-old cultures increased the expression of p75(NGF) (b) over untreated control cells (a); (c, d) are control cultures stained with only the secondary antibody. The nuclei (blue) were stained with DAPI. |
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参考文献: |
1.Stem cells internationalDevelopment of a functional schwann cell phenotype from autologous porcine bone marrow mononuclear cells for nerve repair.2.Stem cells internationalDevelopment of a functional schwann cell phenotype from autologous porcine bone marrow mononuclear cells for nerve repair.3.Neoplasia (New York, N.Y.)Functional sphere profiling reveals the complexity of neuroblastoma tumor-initiating cell model. |
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