IL-6 Receptor (Soluble) Human ELISA Kit ELISA试剂盒,IL-6 Receptor (Soluble) Human ELISA Kit/人IL-6受体(可溶)ELISA试剂盒

2024-10-23

IL-6 Receptor (Soluble) Human ELISA Kit/人IL-6受体(可溶)ELISA试剂盒

货号:BMS214,BMS214TEN

规格:96 Tests,10X96 Tests

价格:6120,34783

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.01 ng/mL

检测范围0.08-5.0 ng/mL

样本类型/体积

血清 10 μL

血浆 10 μL

尿液 20 μL

羊水 20 μL

上清液 20 μL

操作时间

1 hr 20 min

测试时间

2 hr 10 min

Homogenous (no wash)

No

批间变异系数(CV)2.2%
批内变异系数(CV)1.7%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

10 x 96 tests

组份

- 预包被96孔板

- 标准品

- 样品稀释液

- 测定稀释浓缩液

- HRP-共轭检测抗体

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameIL-6 Receptor (CD126)
Protein aliasesCD126, CD126 antigen, gp80, IL-6 receptor subunit alpha, IL-6R 1, Interleukin-6 receptor subunit alpha, Membrane glycoprotein 80

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物HRP
Gene aliasesCD126, gp80, IL-6R-1, IL-6RA, IL6Q, IL6R, IL6RA, IL6RQ
Gene ID(Human) 3570
Gene symbolIL6R
UniProt ID(Human) P08887
The Human Interleukin-6 Receptor (Hu IL-6R) ELISA quantitates Hu IL-6R in human serum, plasma, amniotic fluid, urine or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu IL-6R.人白介素6受体(人IL-6R)ELISA定量了人血清,血浆,羊水,尿液或细胞培养基中的人IL-6R。 该检测试剂盒将专门识别天然和重组的人IL-6R。Principle of the method 方法原理The Human IL-6R solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.人IL-6R固相夹心ELISA(酶联免疫吸附测定)用于测量匹配的抗体对之间结合的靶标量。 已在提供的微孔板的孔中预包被了靶标特异性抗体。 然后将样品,标准液或质控品添加到这些孔中,并与固定的(捕获)抗体结合。 通过添加第二(检测)抗体形成三明治,添加底物溶液,该底物溶液与酶-抗体-靶标复合物反应以产生可测量的信号。 该信号的强度与原始样品中存在的靶标浓度成正比。Rigorous validation 严格验证Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.此ELISA试剂盒的每个制造批次均经过质量测试,其标准包括敏感性,特异性,精密度和批次间一致性。 有关验证的更多信息,请参见手册。Target information 靶标信息Interleukin 6 receptor (IL6R), also known as CD126 (Cluster of Differentiation 126), is a type I cytokine receptor. This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.白介素6受体(IL6R),也称为CD126(分化群126),是I型细胞因子受体。 该基因编码白介素6(IL6)受体复合物的一个亚基。 白介素6是有效的多效细胞因子,可调节细胞生长和分化,并在免疫反应中起重要作用。 IL6受体是一种蛋白质复合物,由该蛋白质和白细胞介素6信号转导子(IL6ST / GP130 / IL6-beta)组成,白细胞介素6信号转导子也是许多其他细胞因子共有的受体亚基。 IL6和该受体的生产失调与许多疾病的发病机理有关,例如多发性骨髓瘤,自身免疫性疾病和前列腺癌。 已经报道了编码不同同工型的选择性剪接的转录变体。 该基因的假基因在9号染色体上发现。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。
数据:

IL-6 Receptor (Soluble) Human ELISA KitRepresentative standard curve for Human IL-6 Receptor ELISA

技术参数
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