Mouse IL-2 ELISA Standard Recombinant Protein/小鼠IL-2 ELISA标准重组蛋白

货号：29-8021-65

规格：4 pack

价格：1454

产品类型：标准品和抗体对

品牌：Thermo Fisher

物种：小鼠

宿主：其它

抗体亚型：其它

荧光染料：其它

应用	Assay-Dependent（Ctrl）；Assay-Dependent（ELISA）
种属反应	Mouse
宿主/亚型	E.coli
分类	Recombinant
类型	Protein
偶联物	Unconjugated
形式	Lyophilized
纯化类型	Affinity chromatography
内含物	no preservative
保存条件	4° C

产品详细信息Description: Mouse IL-2 (also known as TCGF) is an ~17 kDa factor produced mainly by activated CD4+ T cells. IL-2 induces cell cycle progression of resting cells in an antigen non-specific manner and allows clonal expansion of activated T cells. IL-2 also acts on activated B cells, monocytes, NK cells, LAK cells, and on oligodendroglial cells in vitro. In addition, IL-2 plays a role in hematopoiesis, tumor surveillance and anti-inflammatory reactions, and hence is a central regulator of the immune response. Non-glycosylated IL-2 is biologically active.Applications Reported: The Mouse IL-2 Lyophilized Standard is intended to be used as a standard for the Mouse IL-2 Ready-Set-Go! ELISA kit (cat. 88-7024). Typically the standard is run in a series of 7 doubling dilutions from the 'top' standard. Please refer to the Certificate of Analysis included with each ELISA set for instructions on the proper reconstitution and dilution of the lyophilized standard.Note: These are single-use vials. Use one time within 4 hours of reconstitution and discard. Reconstitute and dilute as suggested in the Certificate of Analysis or recovery may not be accurate.Applications Tested: The Mouse IL-2 Lyophilized Standard has been calibrated and tested in the Mouse IL-2 Ready-Set-Go! ELISA kit (cat. 88-7024).Source: E. coli expressed amino acids Ala21-Gln169 of mouse IL-2 accession # MMIL04.靶标信息Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.

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