Human CCL3 (MIP-1 alpha) ELISA Standard Recombinant Protein /人CCL3（MIP-1 α）ELISA标准重组蛋白

货号：39-8238-65

规格：4 pack

价格：0

产品类型：标准品和抗体对

品牌：Thermo Fisher

物种：人

宿主：其它

抗体亚型：其它

荧光染料：其它

应用	Assay-Dependent（Ctrl）；Assay-Dependent（ELISA）
种属反应	Human
宿主/亚型	E.coli
分类	Recombinant
类型	Protein
偶联物	Unconjugated
形式	Liquid
纯化类型	Affinity chromatography
内含物	0.09% sodium azide
保存条件	-80° C

产品详细信息Description: CCL3, also known as Macrophage Inflammatory Protein 1 alpha (MIP-1 alpha), is a member of the CC- subfamily of chemokines and is most closely related to CCL4, or MIP-1 beta. These proteins play critical roles in the recruitment of leukocytes to the site of inflammation. While both CCL3 and CCL4 will attract monocytes, macrophages, and dendritic cells, CCL3 preferentially attracts CD8+ T cells, while CD4+ T cells are more responsive to CCL4. In addition to its chemotactic functions,CCL3 induces inflammatory cytokine secretion, mast cell degranulation, and NK cell activation. It has also been reported to inhibit hematopoetic stem cell proliferation and may be responsible for the maintenance of these cells in a quiescent state. CCL3 signaling is mediated by the G protein-coupled receptors CCR1, CCR4, and CCR5, which are shared with CCL4 and CCL5 (RANTES).Applications Reported: The intended application of the Human CCL3 (MIP-1 alpha) Single-Use ELISA RSG Standard is as a standard for the Human CCL3 ELISA (cat. 88-7035). Typically the standard is run in a series of 7 doubling dilutions from the 'top' standard. Please refer to the Certificate of Analysis included with each ELISA set for instructions on the proper dilution of the recombinant standard.Note: These are single-use vials. Use one time and discard. Dilute as suggested in the Certificate of Analysis, not difficult-to-measure fractions of the suggested volumes or recovery may not be accurate. Use within 6 hours of dilution to top standard concentration.Applications Tested: Human CCL3 (MIP-1 alpha) Single-Use ELISA RSG Standard is reported for use in Human CCL3 (MIP-1 alpha) ELISA Ready-SET-Go!® (cat. 88-7035).Source: E. coli-expressed amino acids Ala27-Ala92, accession # P10147.Storage and handling: For best recovery, quick-spin vial prior to opening. For dilution of current stock, use ELISA Assay Diluent.靶标信息Macrophage inflammatory protein-1a (MIP-1a) is an 8kDa member of the C-C chemokine subfamily. C-C chemokines are chemoattractants and activators for monocytes and T cells. MIP-1a has been identified as one of the major HIV-SFs produced by CD8+ T cells, along with MIP-1b and RANTES.

技术参数

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