ST2 (IL-33R) Human ELISA Kit ELISA试剂盒,ST2 (IL-33R) Human ELISA Kit/人ST2（IL-33R）ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

ST2 (IL-33R) Human ELISA Kit ELISA试剂盒,ST2 (IL-33R) Human ELISA Kit/人ST2（IL-33R）ELISA试剂盒

2024-10-23

ST2 (IL-33R) Human ELISA Kit/人ST2（IL-33R）ELISA试剂盒

货号：BMS2231

规格：96 assays

价格：7217

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：人

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	4.6 pg/mL
检测范围	4.7–300 pg/mL
样本类型/体积	血清 50 μL 血浆 50 μL 细胞裂解液 50 μL
操作时间	1 hr 20 min
测试时间	3 hr 10 min
Homogenous (no wash)	No
批间变异系数（CV）	3.5%
批内变异系数（CV）	4.5%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	96 assays
组份	- 预包被96孔板 - 标准品 - 样品稀释液 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 底物溶液 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	ST2
Protein aliases	DER4, Fit-1, IL-1 R4, IL1R4, IL-1R4, IL-1RL1, IL-33R, Ly84, ST2, ST2L, ST2V, suppression of tumorigenicity 2, T1, growth stimulation-expressed, homolog of mouse growth stimulation-expressed, interleukin 1 receptor-like 1, interleukin 1 receptor-related protein, Interleukin-1 receptor-like 1, Protein ST2
物种（Tested）	人
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	DER4, FIT-1, IL1RL1, IL33R, ST2, ST2L, ST2V, T1
Gene ID	(Human) 9173
Gene symbol	IL1RL1
UniProt ID	(Human) Q01638

The Human ST2 (IL-33R) ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative detection of human ST2 (IL-33R).人ST2（IL-33R）ELISA试剂盒是一种酶联免疫吸附测定法，用于定量检测人ST2（IL-33R）。Target information 靶标信息IL-33R, also known as ST2, is a receptor for IL-33. It is a member of the IL-1 receptor family of innate receptors. Its extracellular domain consists of 3 Ig-like domains that directly interact with its co-receptor IL-1RAcP, and the ligand alarmin, IL-33. IL-33 ligation results in the association of IL-33R complex with its adaptor proteins MyD88, IRAK1, IRAK4 and TRAF6, and activation of the NF-kB, and MAPK pathways. This, in turn, instigates the release of chemokines and cytokines such as IL-5, IL-6, IL-8, and IL-13. Two most common isoforms of IL-33R that result from alternative splicing are ST2L – the membrane bound form, and ST2S – the soluble form. The membrane bound form can be released from the cell surface by proteolytic cleavage. The soluble forms have been suggested to act as decoys dampening the IL-33 signaling. IL-33R is primarily expressed by mast cells, basophils, and eosinophils. In mouse, IL-33R expression has been shown on ILC2 and Th2 cells. IL-33R signaling has been implicated in the number of immune conditions, including allergies, arthritis, atherosclerosis and sepsis.IL-33R也称为ST2，是IL-33的受体。它是先天性受体IL-1受体家族的成员。它的胞外域由3个Ig样域组成，它们直接与其共受体IL-1RAcP和配体警报蛋白IL-33相互作用。 IL-33的连接导致IL-33R复合物与其衔接蛋白MyD88，IRAK1，IRAK4和TRAF6缔合，并激活NF-kB和MAPK途径。反过来，这促使趋化因子和细胞因子如IL-5，IL-6，IL-8和IL-13释放。交替剪接产生的两种最常见的IL-33R亚型为ST2L（膜结合形式）和ST2S（可溶形式）。膜结合形式可以通过蛋白水解切割从细胞表面释放。已经提出可溶形式起抑制IL-33信号传导的诱饵作用。 IL-33R主要由肥大细胞，嗜碱性粒细胞和嗜酸性粒细胞表达。在小鼠中，IL-33R表达已显示在ILC2和Th2细胞上。 IL-33R信号传导与多种免疫状况有关，包括过敏，关节炎，动脉粥样硬化和败血症。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

数据：

ST2 (IL-33R) Human ELISA KitRepresentative standard curve for Human ST2.

技术参数

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ST2 (IL-33R) Human ELISA Kit ELISA试剂盒,ST2 (IL-33R) Human ELISA Kit/人ST2（IL-33R）ELISA试剂盒

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