TNF beta Monoclonal Antibody (LTX-22), eBioscience/TNF beta单克隆抗体(LTX-22)
货号:BMS1046
规格:100 µg
价格:3679
产品类型:抗体和ELISA
品牌:eBioscience
类型: | 单抗 | 同型对照: | |
浓度: | 1 mg/mL | 用法: | Assay-Dependent(ELISA);Assay-Dependent(IHC (F)) |
产品详细信息Description: BMS1046 (LTX-22) is reportded for ELISA and ICH applications.Applications Tested: ELISA, Immunohistochemistry (Frozen).Source: Plant expressed 164 amino acids (Cys32-Thr194) with 16 amino acid Histidine tag. accession NP_002000.Bioactivity: The ED50 of this protein, as measured by proliferation assay of 4MBr5 monkey epthelial cells, is less than or equal to 4 ng/mL. This corresponds to a specific activity of greater than or equal to 2.5 x 10e5 Units/mg.靶标信息TNF beta, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated withsusceptibility to leprosy type 4 and psoriatic arthritis.
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