Rat IL-4 Recombinant Protein, eBioscience/大鼠IL-4重组蛋白

货号：BMS339

规格：10 µg

价格：5441

产品类型：蛋白表达研究

品牌：eBioscience

产品详细信息Description: Interleukin-4 is a potent lymphoid cell growth factor, which stimulates the growth and survivability of certain B and T cells. Recombinant rat IL-4 is a 14 kDa protein containing 121 amino acid residues.Purity: >98%.Molecular Weight: 14.0 kDa.靶标信息Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.

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