SARS-CoV-2 Spike Protein S1 Chimeric Recombinant Human Monoclonal Antibody (H6)

货号：MA5-35940

规格：100μl

价格：9493

产品类型：抗体和染料

品牌：Thermo Fisher

物种：其它

宿主：其它

抗体亚型：IgG1, kappa

克隆号：H6

荧光染料：其它

类型:	单抗	同型对照：
浓度：	0.3 mg/mL	用法：	1:10,000-1:50,000(ELISA)

产品详细信息Recombinant anti-SARS-CoV-2 spike is expressed from 293 cells (HEK293). It is a chimeric monoclonal antibody combining the mouse variable regions with the constant domains of human IgG1.靶标信息It has recently been shown that SARS (severe acute respiratory syndrome) is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness, such as the common cold, in humans. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The glycosilated spike protein (as well as the nucleocapsid protein) can be detected in infected cell culture supernatants with antisera from SARS patients.

数据

SARS-CoV-2 Spike Protein S1 Chimeric Antibody (MA5-35940) in ELISAA functional ELISA was performed to by immobilizing SARS-CoV-2-S1-RBD at 2 µg/mL and using SARS-CoV-2 Spike Protein S1 Chimeric Recombinant Monoclonal Antibody (Product # MA5-35940). The EC50 of the antibody is 13.96 - 16.62 ng/mL.

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