Human CFHR5 ELISA Kit ELISA试剂盒,Human CFHR5 ELISA Kit/人CFHR5 ELISA试剂盒

2024-10-23

Human CFHR5 ELISA Kit/人CFHR5 ELISA试剂盒

货号:EH104RB,EH104RBX5,EH104RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.41 ng/mL

检测范围0.41-100 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameCFHR5
Protein aliasescomplement factor H-related 5, Complement factor H-related protein 5, factor H-related protein 5, FHR-5

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesCFHL5, CFHR5, CFHR5D, FHR-5, FHR5
Gene ID(Human) 81494
Gene symbolCFHR5
UniProt ID(Human) Q9BXR6
Human CFHR5 quantitates human CFHR5 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CFHR5.人CFHR5对血清,血浆,上清液中的人CFHR5进行定量。 该检测试剂盒将专门识别天然和重组人CFHR5。Target information 靶标信息This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS).该基因是1号染色体上小的补体因子H(CFH)基因簇的成员。该基因家族的每个成员均包含多个典型的补体激活调节子的短共有重复序列(SCR)。 该基因编码的蛋白质具有九个SCR,前两个重复具有肝素结合特性,重复5-7内具有肝素结合和C反应蛋白结合特性的区域,C末端重复类似于补体成分3b (C3b)结合域。 该蛋白与C3共定位,以剂量依赖的方式结合C3b,并被募集到被C反应蛋白损伤的组织中。 该基因的等位基因变异与两种不同形式的肾脏疾病相关,但没有因果关系:Ⅱ型膜增生性肾小球肾炎(MPGNII)和溶血性尿毒症(HUS)。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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