Human CMASP-3 ELISA Kit ELISA试剂盒,Human CMASP-3 ELISA Kit/人CMASP-3 ELISA试剂盒

2024-10-23

Human CMASP-3 ELISA Kit/人CMASP-3 ELISA试剂盒

货号:EH113RB,EH113RBX5,EH113RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.6 ng/mL

检测范围150-0.6 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameMASP1
Protein aliasesC4/C2 activating component of Ra-reactive factor, Complement factor MASP-3, Complement-activating component of Ra-reactive factor, mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor), Mannan-binding lectin serine protease 1, Mannan-binding lectin serine protease 1 heavy chain, Mannan-binding lectin serine protease 1 light chain, Mannose-binding lectin-associated serine protease 1, Mannose-binding protein-associated serine protease, MASP-1, Ra-reactive factor serine protease p100, RaRF, Serine protease 5

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliases3MC1, CRARF, CRARF1, MAP1, MAp44, MASP, MASP1, MASP3, PRSS5, RaRF
Gene ID(Human) 5648
Gene symbolMASP1
UniProt ID(Human) P48740
Human CMASP-3 quantitates human CMASP-3 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CMASP-3.人CMASP-3定量检测血清,血浆,上清液中的人CMASP-3。 该检测试剂盒将专门识别天然和重组人CMASP-3。Target information 靶标信息MBL is a key component in immune response in that it can directly trigger neutralization of invading microorganisms by an Ab-independent mechanism. Mutations of human MBL are associated with immunodeficiency resulting from a reduction in the ability of the mutant MBL to initiate complement fixation. In human, three types of MBL-associated serine proteases, MASP-1, MASP-2 and MASP-3, and a truncated form of MASP-2 (small MBL-associated protein; sMAP or MAp19) complex with MBL to activate the lectin pathway of the complement system. MASP-3 is an alternatively spliced product from the MASP-1 gene. The heavy/A chains are identical between MASP-1 and MASP-3 but the light/B chains are entirely different. Activated MASPs subsequently cleave and activate downstream components of the complement pathway.MBL是免疫反应中的关键组成部分,因为它可以通过Ab独立机制直接触发入侵微生物的中和。 人MBL的突变与免疫缺陷有关,该免疫缺陷是由于突变的MBL启动补体固定的能力降低而引起的。 在人类中,三种类型的与MBL相关的丝氨酸蛋白酶MASP-1,MASP-2和MASP-3,以及截短形式的MASP-2(小的与MBL相关的蛋白; sMAP或MAp19)与MBL结合以激活凝集素 补体系统的途径。 MASP-3是MASP-1基因的另一种剪接产物。 MASP-1和MASP-3之间的重链/ A链相同,但轻链/ B链完全不同。 活化的MASP随后裂解并活化补体途径的下游组分。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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