Human Desmoglein-3 ELISA Kit ELISA试剂盒,Human Desmoglein-3 ELISA Kit/人Desmoglein-3 ELISA试剂盒

2024-10-23

Human Desmoglein-3 ELISA Kit/人Desmoglein-3 ELISA试剂盒

货号:EH155RB,EH155RBX5,EH155RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

34 pg/mL

检测范围34-8,000 pg/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameDesmoglein 3
Protein aliases130 kDa pemphigus vulgaris antigen, Cadherin family member 6, Desmoglein-3, PVA

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesCDHF6, DSG3, PVA
Gene ID(Human) 1830
Gene symbolDSG3
UniProt ID(Human) P32926
Human Desmoglein-3 quantitates human Desmoglein-3 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Desmoglein-3.人Desmoglein-3定量测定血清,血浆,上清液中的人Desmoglein-3。 该检测试剂盒将专门识别天然和重组人Desmoglein-3。Target information 靶标信息Desmoglein 3 (Dsg3), also known as Cadherin family member 6 (CDHF6), is a member of the desmosomal cadherin family and plays a critical role in cell-cell adhesion. It is predominately expressed in stratified squamous epithelium, including the skin, oral mucosa, and esophagus. Desmoglein 3 has been characterized as the auto-antigen of pemphigus vulgaris (PV), a life-threatening autoimmune disease. Binding of anti-Desmoglein 3 autoantibodies causes the loss of cell-cell adhesion, which clinically manifests as blisters on the skin and oral mucosa, and histologically as suprabasilar acantholysis.Desmoglein 3(Dsg3),也称为Cadherin家族成员6(CDHF6),是desmosomal cadherin家族的成员,并且在细胞间粘附中起关键作用。 它主要在分层的鳞状上皮中表达,包括皮肤,口腔粘膜和食道。 Desmoglein 3被表征为寻常型天疱疮(PV)的自身抗原,一种威胁生命的自身免疫性疾病。 抗桥粒芯糖蛋白3自身抗体的结合会导致细胞间粘附的丧失,临床上表现为皮肤和口腔粘膜上的水泡,组织学上表现为睑上腺棘皮松解术。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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