Human ALK-1 ELISA Kit ELISA试剂盒,Human ALK-1 ELISA Kit/人ALK-1 ELISA试剂盒

2024-10-23

Human ALK-1 ELISA Kit/人ALK-1 ELISA试剂盒

货号:EH17RB,EH17RBX5,EH17RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.18 ng/mL

检测范围0.18-40 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameACVRL1
Protein aliasesactivin A receptor type II-like 1, activin A receptor type IL, activin A receptor, type II-like kinase 1, Activin receptor-like kinase 1, ALK-1, Serine/threonine-protein kinase receptor R3, SKR3, TGF-B superfamily receptor type I, TSR-I

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesACVRL1, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I
Gene ID(Human) 94
Gene symbolACVRL1
UniProt ID(Human) P37023
Human ALK-1 quantitates human ALK-1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human ALK-1.人ALK-1定量检测血清,血浆,上清液中的人ALK-1。 该检测试剂盒将专门识别天然和重组人ALK-1。Target information 靶标信息The TGF-beta superfamily of ligands exerts its biological activity by binding to heteromeric receptor complexes two types (I and II) of the serine/threonine kinases. ALK1, like the other type I receptors, contains a cysteine rich domain with conserved cysteine spacing in the extracellular region and a glycine and serine rich domain preceding the kinase domain. The reduced human ALK1 monomer has a calculated molecular mass of approximately 37.3 kDa. Due to glycoslyation, the recombinant human protein migrates as a 50-55 kDa protein in SDS-PAGE under reducing conditions. Human and mouse ALK1 share approximately 71% amino acid sequence identity in their extracellular domains. ALK1 is highly expressed in endothelial cells and other vascular tissues.TGF-β配体超家族通过与丝氨酸/苏氨酸激酶的两种(I和II)异源受体复合物结合而发挥其生物学活性。 像其他I型受体一样,ALK1包含一个富含半胱氨酸的结构域,在胞外区域具有保守的半胱氨酸间隔,以及一个位于激酶结构域之前的富含甘氨酸和丝氨酸的结构域。 还原的人ALK1单体的计算分子量约为37.3kDa。 由于糖基化作用,重组人蛋白质在还原条件下以50-55 kDa的蛋白质在SDS-PAGE中迁移。 人和小鼠ALK1在其胞外域中共有大约71%的氨基酸序列同一性。 ALK1在内皮细胞和其他血管组织中高表达。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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